Evidence map›Paper›PMID 31827960›Full record

ArticleCase reports in orthopedics2019

Difficulties of Management of Multiple Synchronous Bone Tumors in Li-Fraumeni Syndrome.

Marine Huby, Laurence Brugières, Eric Mascard, Nathalie Gaspar, Stéphanie Pannier, Jean-Charles Aurégan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marine HubyDepartment of Pediatric Orthopedics, Necker-Enfants Malades Hospital, AP-HP, University Paris Descartes, 149 Rue de Sèvres, 75014 Paris, France.
Laurence BrugièresDepartment of Pediatric and Adolescents Oncology, Gustave Roussy Cancer Campus, Paris Saclay-University, 114 Rue Édouard Vaillant, 94800 Villejuif, France.
Eric MascardDepartment of Pediatric Orthopedics, Necker-Enfants Malades Hospital, AP-HP, University Paris Descartes, 149 Rue de Sèvres, 75014 Paris, France.
Nathalie GasparDepartment of Pediatric and Adolescents Oncology, Gustave Roussy Cancer Campus, Paris Saclay-University, 114 Rue Édouard Vaillant, 94800 Villejuif, France.
Stéphanie PannierDepartment of Pediatric Orthopedics, Necker-Enfants Malades Hospital, AP-HP, University Paris Descartes, 149 Rue de Sèvres, 75014 Paris, France.
Jean-Charles AuréganDepartment of Pediatric Orthopedics, Necker-Enfants Malades Hospital, AP-HP, University Paris Descartes, 149 Rue de Sèvres, 75014 Paris, France.ORCID https://orcid.org/0000-0001-6545-153X
Hôpital Necker-Enfants Malades · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Li-Fraumeni syndrome is a rare inherited disease characterized by the early onset of multiple primary malignant tumors. Sarcomas account for more than 30% of all malignant tumors occurring at pediatric age. Furthermore, it was shown that the rates of second cancer were higher in childhood cancer survivors. We report the case of a patient with Li-Fraumeni syndrome who was referred to us with three synchronous skeletal tumors. This unique situation led to difficulties for the medical team regarding the diagnosis of malignancy and the surgical treatment to propose. The discovery of multiple lesions in the extension assessment underlines the usefulness of whole-body imaging for the follow-up of patients with germline

Identifiers

PMID31827960
PMCPMC6885189
OpenAlexW2988341970

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.