ArticleCase reports in cardiology2019
Ticagrelor-Induced Prolongation of the QTc Interval.
Article in Case reports in cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Safety profile of ticagrelor: an analysis based on literature and database review.BMC cardiovascular disorders · 2026Review
- Electrical Storm Potentially Associated With Ticagrelor: A Case Report and Literature Review.CJC open · 2025Article
- An interesting case series of ticagrelor induced long QTc.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Ticagrelor-Induced Torsades de Pointes following Myocardial Infarction.Case reports in cardiology · 2022Article
- Pleiotropic actions of ticagrelor versus clopidogrel - Do molecular differences translate into superior clinical efficacy after myocardial infarction?International journal of cardiology. Heart & vasculature · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTicagrelor has been accepted as a class I antiplatelet agent in patients undergoing percutaneous coronary angioplasty (PTCA). There have been cases reported on ticagrelor being associated with various cardiac conduction defects. But there is no evidence of QTc prolongation associated with the drug as of yet. CASE PRESENTATION: A 64-year-old male who underwent PTCA was given ticagrelor. A baseline electrocardiogram (ECG) showed a QTc of 402 ms. He returned after 1.5 months with complaints of shortness of breath. An ECG revealed a prolonged QTc of 468 ms. Ticagrelor was discontinued in view of ticagrelor-induced dyspnea and the patient was started on clopidogrel. The other medications were kept unchanged. The patient returned after a month without any complaints. A follow-up ECG showed a reduced QTc of 425 ms.
conclusionWe present a case of ticagrelor-induced QTc prolongation. To our knowledge, this is the first case to be reported on the same. The Naranjo algorithm for causality assessment gave a total score of 6 indicating that the adverse drug reaction falls under the
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Registered trials
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