Evidence map›Paper›PMID 31827721›Full record

ArticleOncotarget2019

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma.

Simone Pacini, Marina Montali, Francesco Mazziotta, Claudia P Schifone, Lucia Macchia, Vittoria Carnicelli, Francesca M Panvini, Serena Barachini, Laura Notarfranchi, Giovanni Battista Previti and 2 more

Abstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Simone PaciniDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.
Marina MontaliDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.
Francesco MazziottaGeNOMEC School of Doctorate, University of Siena, Siena, Italy.
Claudia P SchifoneDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.
Lucia MacchiaDepartment of Laboratory Medicine, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Vittoria CarnicelliDepartment of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Francesca M PanviniInstitute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Serena BarachiniDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.
Laura NotarfranchiDepartment of Medicine and Surgery, Hematology Division, University of Parma, Parma, Italy.
Giovanni Battista PrevitiUnit of Anesthesia and Intensive Care, University of Sassari, Sassari, Italy.
Gabriele BudaDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.
Mario PetriniDepartment of Clinical and Experimental Medicine, Hematology Division, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) progresses mainly in the bone marrow where the involvement of a specific microenvironment plays a critical role in maintaining plasma cell growth, spread, and survival. In active disease, the switch from a pre-vascular/non-active phase to a vascular phase is coupled with the impairment of bone turnover. Previously, we have isolated

Indexed as

angiogenesisbone marrow microenvironmentmesangiogenic progenitor cellsmultiple myelomaosteogenesis

Identifiers

PMID31827721
PMCPMC6887577

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.