Evidence map›Paper›PMID 31827707›Full record

ArticleOxidative medicine and cellular longevity2019

Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish.

Mauro Eugênio Medina Nunes, Lucia Emanueli Schimith, Dennis Guilherme da Costa-Silva, Andressa Rubim Lopes, Luana Paganotto Leandro, Illana Kemmerich Martins, Renata Siqueira de Mello, Diane Duarte Hartmann, Nelson Rodrigues de Carvalho, Pamela Carvalho da Rosa and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Mauro Eugênio Medina NunesOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.ORCID https://orcid.org/0000-0003-3272-3118
Lucia Emanueli SchimithOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Dennis Guilherme da Costa-SilvaOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.ORCID https://orcid.org/0000-0002-5137-4040
Andressa Rubim LopesOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Luana Paganotto LeandroOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Illana Kemmerich MartinsOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Renata Siqueira de MelloOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Diane Duarte HartmannDepartment of Molecular Biology and Biochemistry, Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, 1000 Roraima Avenue, Santa Maria, RS 97105-900, Brazil.
Nelson Rodrigues de CarvalhoOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.
Pamela Carvalho da RosaDepartment of Molecular Biology and Biochemistry, Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, 1000 Roraima Avenue, Santa Maria, RS 97105-900, Brazil.
Rafael TrevisanNicholas School of the Environment, Duke University, Durham, NC 27708, USA.
Richard Thomas Di GiulioNicholas School of the Environment, Duke University, Durham, NC 27708, USA.
Thaís PosserOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.ORCID https://orcid.org/0000-0002-6491-5854
Jeferson Luis FrancoOxidative Stress and Cell Signaling Research Group, Interdisciplinary Center for Biotechnology Research-CIPBIOTEC, Campus São Gabriel, Federal University of Pampa, São Gabriel, RS 97300-000, Brazil.ORCID https://orcid.org/0000-0002-3874-8618
Universidade Federal do Pampa · BRUniversidade Federal de Santa Maria · BRDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Permethrin (PM) is a synthetic pyrethroid insecticide widely used as domestic repellent. Damage effects to nontarget organisms have been reported, particularly in the early stages of development. Studies indicate redox unbalance as secondary PM effect. Therefore, our goal was to investigate the acute PM effects on larval zebrafish. Larvae (6 days postfertilization) were exposed to PM (25-600

Indexed as

AnimalsApoptosisBehavior, AnimalDNA DamageEnergy MetabolismInsecticidesLarvaMitochondriaOxidation-ReductionOxidative StressPermethrinReactive Oxygen SpeciesZebrafishInsecticidesPermethrinReactive Oxygen Species

Identifiers

PMID31827707
PMCPMC6885249
OpenAlexW2983511329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.