Evidence map›Paper›PMID 31827683›Full record

ArticleOxidative medicine and cellular longevity2019

Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome.

Nut Palachai, Jintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukham-Mee

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Synergistic Effects of Anthocyanin-EnrichedFoods (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Synergistic Antioxidant Effects of C3G-EnrichedInternational journal of molecular sciences · 2025
    Article
  5. SIRT1-Mediated Epigenetic Protective Mechanisms of Phytosome-EncapsulatedInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Food chemistry: X · 2024
    Article
  8. Article
  9. The Potential of DehydratedPharmaceuticals (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Polyphenols and Polysaccharides fromFoods (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nut PalachaiDepartment of Physiology and Graduate School (Neuroscience Program), Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Jintanaporn WattanathornIntegrative Complementary Alternative Medicine Research, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID https://orcid.org/0000-0002-7383-2348
Supaporn MuchimapuraIntegrative Complementary Alternative Medicine Research, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID https://orcid.org/0000-0001-7756-1955
Wipawee Thukham-MeeIntegrative Complementary Alternative Medicine Research, Khon Kaen University, Khon Kaen 40002, Thailand.
Khon Kaen University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the antimetabolic syndrome effect of mulberry and ginger together with the advantages of the synergistic effect and phytosome encapsulation technique, we hypothesized that phytosome containing the combined extracts of mulberry and ginger (PMG) should be able to manage MetS. PMG was developed and assessed the phenolic content and biological activities associated with the pathophysiology of MetS. The antimetabolic syndrome effect and the possible underlying mechanisms in the animal model of MetS were also assessed. Male Wistar rats induced MetS by subjecting to a 16-week high-carbohydrate high-fat diet. MetS rats were orally given PMG at doses of 50, 100, and 200 mg/kg for 21 days. They were determined metabolic parameter changes in serum, histomorphology changes of adipose tissue, the inflammatory cytokines such as IL-6 and TNF-

Indexed as

Adipose TissueAnimalsAntioxidantsBlood GlucoseCholesterol, LDLDiet, High-FatDisease Models, AnimalHistone Deacetylase 3Histone DeacetylasesMaleMetabolic SyndromeMorusOxidative StressPlant ExtractsPPAR gammaRatsAntioxidantsBlood GlucoseCholesterol, LDLHistone Deacetylase 3Histone DeacetylasesPlant ExtractsPPAR gammaTumor Necrosis Factor-alpha

Identifiers

PMID31827683
PMCPMC6881582
OpenAlexW2984160887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.