Evidence map›Paper›PMID 31827670›Full record

ArticleOxidative medicine and cellular longevity2019

5

Tomasz Wielkoszyński, Jolanta Zalejska-Fiolka, Joanna K Strzelczyk, Aleksander J Owczarek, Armand Cholewka, Aneta Krawczyk, Agata Stanek

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. 5Oxidative medicine and cellular longevity · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tomasz WielkoszyńskiHigher School of Strategic Planning in Dąbrowa Górnicza, Kościelna 6 St., 41-300 Dąbrowa Górnicza, Poland.ORCID https://orcid.org/0000-0002-8823-3313
Jolanta Zalejska-FiolkaMedical University of Silesia, School of Medicine with the Division of Dentistry in Zabrze, Department of Biochemistry, Jordana 19 St., 41-808 Zabrze, Poland.ORCID https://orcid.org/0000-0002-3879-6548
Joanna K StrzelczykMedical University of Silesia, School of Medicine with the Division of Dentistry in Zabrze, Department of Medical and Molecular Biology, Jordana 19 St., 41-808 Zabrze, Poland.ORCID https://orcid.org/0000-0002-3686-5685
Aleksander J OwczarekMedical University of Silesia, School of Pharmacy with the Division of Laboratory Medicine, Department of Statistics, Department of Instrumental Analysis, Ostrogórska 30 St, Sosnowiec 41-209, Poland.ORCID https://orcid.org/0000-0003-1179-6932
Armand CholewkaUniversity of Silesia, Department of Medical Physics, Chelkowski Institute of Physics, Uniwersytecka 4 St., 40-007 Katowice, Poland.ORCID https://orcid.org/0000-0003-3998-7677
Aneta KrawczykMedical Center and Lab, Aleja Marszałka Piłsudskiego 10, 41-300 Dąbrowa Górnicza, Poland.
Agata StanekMedical University of Silesia, School of Medicine with the Division of Dentistry in Zabrze, Department of Internal Medicine, Angiology and Physical Medicine, Batorego 15 St., 41-902 Bytom, Poland.ORCID https://orcid.org/0000-0001-6939-9898
Medical University of Silesia · PLInstitute of Physics · PLWSB University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCholesterol oxidation products have an established proatherogenic and cytotoxic effect. An increased exposure to these substances may be associated with the development of atherosclerosis and cancers. Relatively little, though, is known about the effect of phytosterol oxidation products, although phytosterols are present in commonly available and industrial food products. Thus, the aim of the research was to assess the effect of 5 MATERIAL AND

methodsThe animals were divided into 3 groups and exposed to nutritional sterols by receiving feed containing 5

resultsDuring the experiment, the levels of lipid peroxidation products increased, such as CD and anti-7-ketocholesterol antibodies. At the same time, the plasma levels of FRAP and serum activity of PON1 decreased alongside the reduced activity of GPx, GR, and SOD in RBCs. There was no effect of the studied compounds on the plasma MDA levels or on the activity of CAT and GST in RBCs.

conclusionsBoth 5

Indexed as

DietAnimalsAntibodiesAntioxidantsAryldialkylphosphataseCatalaseCholesterolErythrocytesGlutathione PeroxidaseGlutathione ReductaseKetocholesterolsMaleMalondialdehydeOxidative StressPhytosterolsRats5,6-epoxycholesterol7-ketocholesterolAntibodiesAntioxidantsAryldialkylphosphataseCatalaseCholesterolGlutathione PeroxidaseGlutathione ReductaseKetocholesterolsMalondialdehydePhytosterolsSuperoxide Dismutase

Identifiers

PMID31827670
PMCPMC6881747
OpenAlexW2983934866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.