Evidence map›Paper›PMID 31827642›Full record

ArticleDisease markers2019

Adrian Groh, Kirsten Jahn, Michael Gröschl, Thomas Hillemacher, Johannes Kornhuber, Stefan Bleich, Helge Frieling, Annemarie Heberlein

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adrian GrohDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.ORCID https://orcid.org/0000-0002-4407-3557
Kirsten JahnDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.
Michael GröschlCelerion Switzerland AG, Switzerland.
Thomas HillemacherDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.
Johannes KornhuberDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Germany.ORCID https://orcid.org/0000-0002-8096-3987
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.
Helge FrielingDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.ORCID https://orcid.org/0000-0001-5146-9720
Annemarie HeberleinDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Center for Addiction Research, Medical School Hanover, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEParacelsus Medizinische Privatuniversität · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NGF and VEGF are known to be involved in different psychiatric diseases. In order to verify hints from basic research that both neurotrophines interact with each other, serum levels of NGF and VEGF were measured in a cohort of 33 healthy individuals and correlated. NGF level was 126.30 pg/mL (±155.43), and VEGF level was 57.28 pg/mL (±44.48). Both factors were significantly correlated, confirming their interaction and legitimising the usage of their respective ratio (0.8 (±0.42)) as a less varying additional marker in prospective studies.

Indexed as

AdultCohort StudiesFemaleHealthy VolunteersHumansMaleNerve Growth FactorProtein Interaction Domains and MotifsVascular Endothelial Growth Factor ANerve Growth FactorNGF protein, humanVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID31827642
PMCPMC6885270
OpenAlexW2983639359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.