Evidence map›Paper›PMID 31827638›Full record

ArticleDisease markers2019

Overexpression of UDP-Glucose 4-Epimerase Is Associated with Differentiation Grade of Gastric Cancer.

Maria de Fátima Deodato de Souza, Antônio Felix da Silva Filho, Amanda Pinheiro de Barros Albuquerque, Michael Williams Leal Quirino, Mário Sérgio de Souza Albuquerque, Marina Ferraz Cordeiro, Mário Rino Martins, Ivan da Rocha Pitta, Antônio Roberto Lucena-Araujo, Maira Galdino da Rocha Pitta and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Maria de Fátima Deodato de SouzaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Antônio Felix da Silva FilhoLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Amanda Pinheiro de Barros AlbuquerqueLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Michael Williams Leal QuirinoLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Mário Sérgio de Souza AlbuquerqueLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Marina Ferraz CordeiroLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Mário Rino MartinsHospital do Câncer de Pernambuco-HCP, Recife, PE, Brazil.
Ivan da Rocha PittaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Antônio Roberto Lucena-AraujoDepartamento de Genetica, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Maira Galdino da Rocha PittaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.ORCID https://orcid.org/0000-0001-5881-0338
Moacyr Jesus Barreto de Melo RêgoLaboratório de Imunomodulação e Novas Abordagens Terapêuticas-LINAT/Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino-NUPIT SG, Universidade Federal de Pernambuco, Recife, PE, Brazil.ORCID https://orcid.org/0000-0002-1883-6012
Universidade Federal de Pernambuco · BRHospital de Câncer de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The UDP-glucose 4-epimerase (GALE) is a glycosyltransferase, which acts on protein and lipid glycosylation in normal and neoplastic cells. This study is aimed at investigating the differential tissue expression of GALE and its possible association with clinical-pathological parameters and the outcome of gastric adenocarcinoma patients. Seventy-one patients were evaluated in relation to GALE expression by immunohistochemistry. Our results showed that 48 (67.6%) patients were GALE positive and 23 (32.4%) negative. Positive staining was present on well-differentiated and moderate-differentiated histological grade of gastric adenocarcinomas (

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overBiomarkers, TumorCell DifferentiationCombined Modality TherapyFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalStomach NeoplasmsBiomarkers, TumorUDPglucose 4-Epimerase

Identifiers

PMID31827638
PMCPMC6886318
OpenAlexW2990736218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.