Evidence map›Paper›PMID 31827446›Full record

ArticleFrontiers in physiology2019

Neuromuscular Electrical Stimulation Induces Skeletal Muscle Fiber Remodeling and Specific Gene Expression Profile in Healthy Elderly.

Rosa Mancinelli, Luana Toniolo, Ester Sara Di Filippo, Christian Doria, Mariangela Marrone, Camilla Reina Maroni, Vittore Verratti, Danilo Bondi, Lisa Maccatrozzo, Tiziana Pietrangelo and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05997095 (Optimisation of Post-operative Electrical Muscle Stimulation), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05997095 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Optimisation of Post-operative Electrical Muscle Stimulation (PoEMS) to Stimulate Muscle Protein Synthesis in Humans

TypeinterventionalSponsorUniversity of NottinghamRan2023 to 2025Enrolled10ConditionsSkeletal Muscle AtrophyArmsNeuromuscular electrical stimulation (NMES/0
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Effects of Focused Vibrations on Human Satellite Cells.International journal of molecular sciences · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rosa MancinelliDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Luana TonioloDepartment of Biomedical Sciences, University of Padova, Padua, Italy.
Ester Sara Di FilippoDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Christian DoriaDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Mariangela MarroneDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Camilla Reina MaroniDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Vittore VerrattiLaboratory of Functional Evaluation, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Danilo BondiDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Lisa MaccatrozzoDepartment of Comparative Biomedicine and Food Science, University of Padova, Padua, Italy.
Tiziana PietrangeloDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Stefania FulleDepartment of Neuroscience Imaging and Clinical Sciences, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
University of Chieti-Pescara · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle aging is a multifactorial process strictly related to progressive weakness. One of the results that were focused on was the fiber phenotype modification and their loss. The physiological muscle recruitment to contraction, basically prosecuted under volitional control, can also be engaged by means of Neuromuscular Electrical Stimulation (NMES). Knowing that the NMES is effective in improving muscle strength in active healthy elderly, the aim was to investigate which physiological modifications were able to produce in the

Indexed as

gene expressionmaximal voluntary contractionneuromuscular electrical stimulationoxidative stresssingle fiber mechanic

Identifiers

PMID31827446
PMCPMC6890722
OpenAlexW2991534990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.