ArticleFrontiers in neuroanatomy2019
Transcriptomic Characterization of the Human Insular Cortex and Claustrum.
Article in Frontiers in neuroanatomy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Proteomic insights into the macaque insular parcellation based on structural connectivity gradients.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning-Based Advanced Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Let's focus on the insula in addiction: A refined anatomical exploration of insula in severe alcohol and cocaine use disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Article
- Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex.Biology of sex differences · 2024Article
- A simple and reliable method for claustrum localization across age in mice.Molecular brain · 2024Article
- Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortex.Research square · 2023Article
- Proteomic Profiling Reveals Specific Molecular Hallmarks of the Pig Claustrum.Molecular neurobiology · 2023Article
- Microstructural imaging and transcriptomics of the basal forebrain in first-episode psychosis.Translational psychiatry · 2022Article
- Structural alterations of the insula in depression patients - A 7-Tesla-MRI study.NeuroImage. Clinical · 2022Article
- The mystery of claustral neural circuits and recent updates on its role in neurodegenerative pathology.Behavioral and brain functions : BBF · 2021Review
- Changing the Cortical Conductor's Tempo: Neuromodulation of the Claustrum.Frontiers in neural circuits · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The insular cortex has been linked to a multitude of functions. In contrast, the nearby claustrum is a densely connected subcortical region with unclear function. To view the insula-claustrum region from the molecular perspective we analyzed the transcriptomic profile of these areas in six adult and four fetal human brains. We identified marker genes with specific expression and performed transcriptome-wide tests for enrichment of biological processes, molecular functions, and cellular components. In addition, specific insular and claustral expression of genes pertaining to diseases, addiction, and depression was tested. At the anatomical level, we used brain-wide analyses to determine the specificity of our results and to determine the transcriptomic similarity of the insula-claustrum region. We found
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