ArticleFrontiers in neuroscience2019
Dynamics of Vagal Activity Due to Surgery and Subsequent Rehabilitation.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07464860 (A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty: A Randomized Controlled Feasibility Trial
Who cites it
14 citing papers in PubMed.
- Cardiorespiratory Interaction and Autonomic Sleep Quality Improve during Sleep in Beds Made fromInternational journal of environmental research and public health · 2021Trial
- Psychological Resilience in Surgery: Psychobiological Pathways, Clinical Impact, and Perioperative Modulation-A Narrative Review.Journal of personalized medicine · 2026Review
- A Randomized Controlled Trial of Paula Method Versus Gum Chewing for Gastrointestinal Reactivation After Cesarean Delivery.Journal of clinical medicine · 2026Article
- Preoperative vagal activity predicts clinical outcomes after total knee replacement.Experimental and therapeutic medicine · 2024Article
- The brain-heart-immune axis: a vago-centric framework for predicting and enhancing resilient recovery in older surgery patients.Bioelectronic medicine · 2024Article
- Time-course of heart rate variability after total hip arthroplasty.Journal of clinical monitoring and computing · 2024Article
- Effects of perioperative clinical hypnosis on heart rate variability in patients undergoing oncologic surgery: secondary outcomes of a randomized controlled trial.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Changes in the autonomic cardiorespiratory activity in parturient women with severe and moderate features of preeclampsia.Frontiers in immunology · 2023Article
- The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30 - April 3, 2022 at the University of Padua and Thermae of Euganean Hills, Padua, Italy: The collection of abstracts.European journal of translational myology · 2022Article
- Pulse respiration quotient as a measure sensitive to changes in dynamic behavior of cardiorespiratory coupling such as body posture and breathing regime.Frontiers in physiology · 2022Article
- The Neuroimmune Response to Surgery - An Exploratory Study of Trauma-Induced Changes in Innate Immunity and Heart Rate Variability.Frontiers in immunology · 2022Observational
- Comparison of patient- and clinician-reported outcome measures in lower back rehabilitation: introducing a new integrated performance measure (t2D).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Time Window Determination for Inference of Time-Varying Dynamics: Application to Cardiorespiratory Interaction.Frontiers in physiology · 2020Article
- Heart Rhythm Analyzed via Shapelets Distinguishes Sleep From Awake.Frontiers in physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVagal activity is critical for maintaining key body functions, including the stability of inflammatory control. Its weakening, such as in the aftermatch of a surgery, leaves the body vulnerable to diverse inflammatory conditions, including sepsis.
methodsVagal activity can be measured by the cardiorespiratory interaction known as respiratory sinus arrhythmia or high-frequency heart-rate variability (HRV). We examined the vagal dynamics before, during and after an orthopedic surgery. 39 patients had their HRV measured around the period of operation and during subsequent rehabilitation. Measurements were done during 24 h circadian cycles on ten specific days. For each patient, the circadian vagal activity was calculated from HRV data.
resultsOur results confirm the deteriorating effect of surgery on vagal activity. Patients with stronger pre-operative vagal activity suffer greater vagal withdrawal during the peri-operative phase, but benefit from stronger improvements during post-operative period, especially during the night. Rehabilitation seems not only to efficiently restore the vagal activity to pre-operative level, but in some cases to actually improve it. DISCUSSION: Our findings indicate that orthopedic rehabilitation has the potential to strengthen the vagal activity and hence boost inflammatory control. We conclude that providing a patient with a vagal reinforcement procedure
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.