Evidence map›Paper›PMID 31827248›Full record

ReviewMolecular psychiatry2020

CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.

Qiang Xu, Lining Guo, Jingliang Cheng, Meiyun Wang, Zuojun Geng, Wenzhen Zhu, Bing Zhang, Weihua Liao, Shijun Qiu, Hui Zhang and 27 more

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Linking the exposome to the brain-behaviour phenotype.Nature reviews. Neuroscience · 2026
    Review
  5. Article
  6. Empirical validation of race-neutral normative brain morphometry models across ethnoracially diverse populations.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. Genome-Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  10. Article
  11. Article
  12. Human development, inequality, and their associations with brain structure across 29 countries.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 20 institutions in 2 countries.

Qiang XuDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Lining GuoDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Jingliang ChengDepartment of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Meiyun WangDepartment of Radiology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, 450003, Zhengzhou, China.
Zuojun GengDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, 050000, Shijiazhuang, China.
Wenzhen ZhuDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China.
Bing ZhangDepartment of Radiology, Drum Tower Hospital, Medical School of Nanjing University, 210008, Nanjing, China.
Weihua LiaoDepartment of Radiology, Xiangya Hospital, Central South University, 410008, Changsha, China.
Shijun QiuDepartment of Medical Imaging, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 510405, Guangzhou, China.
Hui ZhangDepartment of Radiology, The First Hospital of Shanxi Medical University, 030001, Taiyuan, China.
Xiaojun XuDepartment of Radiology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, 310009, Hangzhou, China.
Yongqiang YuDepartment of Radiology, The First Affiliated Hospital of Anhui Medical University, 230022, Hefei, China.
Bo GaoDepartment of Radiology, Yantai Yuhuangding Hospital, 264000, Yantai, China.
Tong HanDepartment of Radiology, Tianjin Huanhu Hospital, 300350, Tianjin, China.
Zhenwei YaoDepartment of Radiology, Huashan Hosptial, Fudan University, 200040, Shanghai, China.
Guangbin CuiFunctional and Molecular Imaging Key Lab of Shaanxi Province & Department of Radiology, Tangdu Hospital, The Military Medical University of PLA Airforce (Fourth Military Medical University), 710038, Xi'an, China.
Feng LiuDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Wen QinDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Quan ZhangDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China.
Mulin Jun LiCollaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China.ORCID http://orcid.org/0000-0003-3598-3679
Meng LiangSchool of Medical Imaging, Tianjin Medical University, 300203, Tianjin, China.
Feng ChenDepartment of Radiology, Hainan General Hospital, 570311, Haikou, China.ORCID http://orcid.org/0000-0002-9129-7895
Junfang XianDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China.
Jiance LiDepartment of Radiology, The First Affiliated Hospital of Wenzhou Medical University, 325000, Wenzhou, China.
Jing ZhangDepartment of Magnetic Resonance, Lanzhou University Second Hospital, 730050, Lanzhou, China.
Xi-Nian ZuoDepartment of Psychology, University of Chinese Academy of Sciences (CAS), 100049, Beijing, China.ORCID http://orcid.org/0000-0001-9110-585X
Dawei WangDepartment of Radiology, Qilu Hospital of Shandong University, 250012, Jinan, China.
Wen ShenDepartment of Radiology, Tianjin First Center Hospital, 300192, Tianjin, China.
Yanwei MiaoDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, 116011, Dalian, China.
Fei YuanDepartment of Radiology, Pingjin Hospital, Logistics University of Chinese People's Armed Police Forces, 300162, Tianjin, China.
Su LuiDepartment of Radiology, The Center for Medical Imaging, West China Hospital of Sichuan University, 610041, Chengdu, China.
Xiaochu ZhangCAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, 230026, Hefei, China.ORCID http://orcid.org/0000-0002-7541-0130
Kai XuDepartment of Radiology, The Affiliated Hospital of Xuzhou Medical University, 221006, Xuzhou, China.
Long Jiang ZhangDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, 210002, Nanjing, China.
Zhaoxiang YeDepartment of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, 300060, Tianjin, China.
Chunshui YuDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 300052, Tianjin, China. chunshuiyu@tmu.edu.cn.
CHIMGEN Consortium
Tianjin Medical University General Hospital · CNTianjin Medical University · CNAir Force Medical University · CNAnhui Medical University · CNBeijing Tongren Hospital · CNCentral South University · CNDalian Medical University · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Zhengzhou University · CNFudan University · CNHainan General Hospital · CNHebei Medical University · CNInstitute of Psychology, Chinese Academy of Sciences · CNLanzhou University Second Hospital · CNNanjing Drum Tower Hospital · CNNanjing General Hospital of Nanjing Military Command · CNPingjin Hospital · CNQilu Hospital of Shandong University · CNSecond Affiliated Hospital of Zhejiang University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese neuroimaging genetics cohort and aims to identify genetic and environmental factors and their interactions that are associated with neuroimaging and behavioral phenotypes. This study prospectively collected genomic, neuroimaging, environmental, and behavioral data from more than 7000 healthy Chinese Han participants aged 18-30 years. As a pioneer of large-sample neuroimaging genetics cohorts of non-Caucasian populations, this cohort can provide new insights into ethnic differences in genetic-neuroimaging associations by being compared with Caucasian cohorts. In addition to micro-environmental measurements, this study also collects hundreds of quantitative macro-environmental measurements from remote sensing and national survey databases based on the locations of each participant from birth to present, which will facilitate discoveries of new environmental factors associated with neuroimaging phenotypes. With lifespan environmental measurements, this study can also provide insights on the macro-environmental exposures that affect the human brain as well as their timing and mechanisms of action.

Indexed as

AdultAsian PeopleBrainChinaCohort StudiesEthnicityFemaleGenomicsHealthy VolunteersHumansMaleNeuroimagingProspective StudiesResearch

Identifiers

PMID31827248
PMCPMC7042768
OpenAlexW2995219537

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.