Evidence map›Paper›PMID 31827153›Full record

ArticleScientific reports2019

Population relationships based on 170 ancestry SNPs from the combined Kidd and Seldin panels.

Andrew J Pakstis, William C Speed, Usha Soundararajan, Haseena Rajeevan, Judith R Kidd, Hui Li, Kenneth K Kidd

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Genetic ancestry shapes dengue virus infection in human skin explants.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  5. Review
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  8. Review
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  10. Article
  11. Overview of frequent pattern mining.Genomics & informatics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew J PakstisDepartment of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA.
William C SpeedDepartment of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA.
Usha SoundararajanDepartment of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA.
Haseena RajeevanCenter for Medical Informatics, Yale University School of Medicine, New Haven, CT, 06520, USA.
Judith R KiddDepartment of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA.
Hui LiMinistry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Kenneth K KiddDepartment of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA. Kenneth.Kidd@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The benefits of ancestry informative SNP (AISNP) panels can best accrue and be properly evaluated only as sufficient reference population data become readily accessible. Ideally the set of reference populations should approximate the genetic diversity of human populations worldwide. The Kidd and Seldin AISNP sets are two panels that have separately accumulated thus far the largest and most diverse collections of data on human reference populations from the major continental regions. A recent tally in the ALFRED allele frequency database finds 164 reference populations available for all the 55 Kidd AISNPs and 132 reference populations for all the 128 Seldin AISNPs. Although much more of the genetic diversity in human populations around the world still needs to be documented, 81 populations have genotype data available for all 170 AISNPs in the union of the Kidd and Seldin panels. In this report we examine admixture and principal component analyses on these 81 worldwide populations and some regional subsets of these reference populations to determine how well the combined panel illuminates population relationships. Analyses of this dataset that focused on Native American populations revealed very strong cluster patterns associated with many of the individual populations studied.

Indexed as

Gene FrequencyGenetic VariationGenotypePolymorphism, Single NucleotideDatabases, GeneticGenetics, PopulationHigh-Throughput Nucleotide SequencingHumans

Identifiers

PMID31827153
PMCPMC6906462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.