Evidence map›Paper›PMID 31826998›Full record

ArticleJournal of virology2020

Invasion of Herpes Simplex Virus 1 into Murine Dermis: Role of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors during Aging.

Lisa Wirtz, Maureen Möckel, Dagmar Knebel-Mörsdorf

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Bio-protocol · 2022
    Article
  3. Article
  4. Article
  5. Journal of virology · 2021
    Article
  6. Review
  7. Herpes Simplex Virus Type 1 Interactions with the Interferon System.International journal of molecular sciences · 2020
    Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa WirtzCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.
Maureen MöckelCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.
Dagmar Knebel-MörsdorfCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany dagmar.moersdorf@uni-koeln.de.
University Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin is a major target tissue of herpes simplex virus 1 (HSV-1), and we are only beginning to understand how individual receptors contribute to the initiation of infection in tissue. We recently demonstrated the impact of the receptors nectin-1 and herpesvirus entry mediator (HVEM) for entry of HSV-1 into murine epidermis. Here, we focus on viral invasion into the dermis, a further critical target tissue

Indexed as

AgingAnimalsDermisDisease Models, AnimalEpidermisHerpes SimplexHerpesvirus 1, HumanHumansMiceMice, Inbred C57BLMice, KnockoutNectinsReceptors, Cell SurfaceReceptors, Tumor Necrosis Factor, Member 14SkinVirus InternalizationNectin1 protein, mouseNectinsReceptors, Cell SurfaceReceptors, Tumor Necrosis Factor, Member 14dermal fibroblastsex vivo infectionHSV-1HVEMmurine dermisnectin-1viral entry

Identifiers

PMID31826998
PMCPMC7022365
OpenAlexW2995598761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.