Evidence map›Paper›PMID 31826989›Full record

ArticleJournal of virology2020

Herpes Simplex Virus 1-Specific CD8

Benjamin R Treat, Sarah M Bidula, Anthony J St Leger, Robert L Hendricks, Paul R Kinchington

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Role of IL-27 in HSV-1-Induced Herpetic Stromal Keratitis.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Benjamin R TreatGraduate Program in Microbiology and Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sarah M BidulaGraduate Program in Molecular Virology and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Anthony J St LegerDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2547-200X
Robert L HendricksDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Paul R KinchingtonDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA kinchingtonp@upmc.edu.ORCID 0000-0002-1901-9970
University of Pittsburgh · US

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
ROLE OF CYTOTOXIC LYMPHOCYTES IN HSV-1 CORNEAL LESIONSR01EY005945 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HENDRICKS, ROBERT L · 1986 to 2017
$8.3M
Viral Persistence and PathogenesisT32AI049820 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DELUCA, NEAL A. · 2001 to 2024
$5.5M
Contribution of Sympathetic Nerves to Herpes Stromal KeratitisR01EY026891 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ANTHONY J ST LEGER · 2017 to 2026
$4.7M
Gene Expression in HSV-1 Latency After Corneal InfectionR01EY015291 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KINCHINGTON, PAUL R. · 2004 to 2013
$2.9M
Microbiome-dependent modulation of ocular immunity and the implications for infectious R00EY025761 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ST LEGER, ANTHONY J · 2018 to 2020
$862k
NEI NIH HHS P30 EY008098NEI NIH HHS R00 EY025761NEI NIH HHS R01 EY005945NEI NIH HHS R01 EY015291NEI NIH HHS R01 EY026891NIAID NIH HHS T32 AI049820
6 · The paper itself

Abstract

Reactivation of herpes simplex virus 1 (HSV-1) from neurons in sensory ganglia such as the trigeminal ganglia (TG) is influenced by virus-specific CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesChlorocebus aethiopsDisease Models, AnimalFemaleGangliaGanglia, SensoryHerpes SimplexHerpesvirus 1, HumanImmunodominant EpitopesKeratitis, HerpeticKineticsMiceMice, Inbred C57BLTrigeminal GanglionVero Cellsglycoprotein B, SimplexvirusImmunodominant EpitopesViral Envelope ProteinsCD8 T cellHSV-1immunodominancelatency

Identifiers

PMID31826989
PMCPMC7022356
OpenAlexW2994106020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.