Evidence map›Paper›PMID 31826854›Full record

ArticleBiology open2020

Notch signaling governs the expression of glypican Dally to define the stem cell niche.

Songhua Zhao, Chan Wu, Zhiyang Gao, Xin Li, Zheng Guo, Zhaohui Wang

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Songhua ZhaoState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100049, China.
Chan WuThe University of Chinese Academy of Sciences, Beijing 100049, China.
Zhiyang GaoState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100049, China.
Xin LiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100049, China.
Zheng GuoThe University of Chinese Academy of Sciences, Beijing 100049, China.
Zhaohui WangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100049, China zhwang@genetics.ac.cn.ORCID 0000-0002-5872-5712
Chinese Academy of Sciences · CNInstitute of Genetics and Developmental Biology · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular glypicans play pivotal roles in organogenesis, stem cell maintenance and cancer development. However, the growth phenotypes associated with different levels of glypican are not consistent in development or tumorigenesis. This requires clarification on how the spatial patterns of glypican relate to the distribution of signaling molecules in different cellular contexts, and how glypican expression is regulated. We have previously reported that Dally, one of the glypican members in

Indexed as

Signal TransductionStem Cell NicheAnimalsDrosophilaDrosophila ProteinsGene Expression RegulationGlypicansImmunohistochemistryMembrane GlycoproteinsProteoglycansReceptors, NotchStem CellsTranscription, Geneticdally protein, DrosophilaDrosophila ProteinsGlypicansMembrane GlycoproteinsProteoglycansReceptors, NotchGlypicanHuman GPCNotch signalingStem cell niche

Identifiers

PMID31826854
PMCPMC6994927
OpenAlexW2996657336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.