Evidence map›Paper›PMID 31826696›Full record

ArticleJournal of dental research2020

Dimeric Proanthocyanidins on the Stability of Dentin and Adhesive Biointerfaces.

A A Leme-Kraus, R S Phansalkar, M C Dos Reis, B Aydin, A B S Sousa, Y Alania, J McAlpine, S N Chen, G F Pauli, A K Bedran-Russo

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Optimization of dental adhesive interfaces using tissue biomodulation with DESIGNER biopolymers.Dental materials : official publication of the Academy of Dental Materials · 2025
    Article
  9. Review
  10. Article
  11. Prodelphinidins enhance dentin matrix properties and promote adhesion to methacrylate resin.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Proanthocyanidin encapsulation for sustained bioactivity in dentin bioadhesion: A two-year study.Dental materials : official publication of the Academy of Dental Materials · 2022
    Article
  19. Article
  20. Unveiling structure-activity relationships of proanthocyanidins with dentin collagen.Dental materials : official publication of the Academy of Dental Materials · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

A A Leme-KrausDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
R S PhansalkarDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
M C Dos ReisDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
B AydinDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
A B S SousaDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
Y AlaniaDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
J McAlpineDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
S N ChenDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
G F PauliDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
A K Bedran-RussoDepartment of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0002-3670-9519
University of Illinois Chicago · US

Funding

Biomodification of Dentin Matrix StructureR01DE021040 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2011 to 2015
$2.1M
Biomodification of Dentin Matrix StructureR56DE021040 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2017 to 2017
$648k
NIDCR NIH HHS R01 DE021040NIDCR NIH HHS R56 DE021040
6 · The paper itself

Abstract

A dentin biomodification strategy with selective proanthocyanidin (PAC)-enriched extracts reinforces dentin and dentin-resin interfaces. Enrichment of the extracts according to the degree of polymerization allows exploration of bioactive principles of PACs and structure-activity relationships. This study investigated the sustained dentin matrix biomodification and dentin-resin bioadhesion of 2 fractions consisting exclusively of B-type PAC dimers with or without a single galloyl motif (specifically, DIMER

Indexed as

Dental BondingDentinGrape Seed ExtractProanthocyanidinsCollagenDental CementsDentin-Bonding AgentsMaterials TestingTensile StrengthCollagenDental CementsDentin-Bonding AgentsGrape Seed ExtractProanthocyanidinsbioadhesionbiomodificationbiostabilityextracellular matrixgrape seed extracttype I collagen

Identifiers

PMID31826696
PMCPMC7431887
OpenAlexW2995810804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.