Evidence map›Paper›PMID 31825656›Full record

ArticleAmerican journal of physiology. Cell physiology2020

Activation of the PKA signaling pathway stimulates oxalate transport by human intestinal Caco2-BBE cells.

Donna Arvans, Altayeb Alshaikh, Mohamed Bashir, Christopher Weber, Hatim Hassan

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Sel1-like proteins and peptides are the majorAmerican journal of physiology. Cell physiology · 2023
    Article
  3. Oxalate secretion is stimulated by a cAMP-dependent pathway in the mouse cecum.Pflugers Archiv : European journal of physiology · 2023
    Article
  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donna ArvansDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Altayeb AlshaikhDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Mohamed BashirDepartment of Medicine, The University of Chicago, Chicago, Illinois.
Christopher WeberDepartment of Pathology, The University of Chicago, Chicago, Illinois.
Hatim HassanDepartment of Medicine, The University of Chicago, Chicago, Illinois.
University of Chicago · US

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI PEKOW, JOEL · 1990 to 2025
$29.8M
Mechanisms of Regulation of Anion Exchanger SLC26A6K08DK067245 · NIDDK · YALE UNIVERSITY · PI HASSAN, HATIM A · 2005 to 2010
$765k
NIDDK NIH HHS K08 DK067245NIDDK NIH HHS P30 DK042086
6 · The paper itself

Abstract

Most kidney stones are composed of calcium oxalate, and small increases in urine oxalate enhance the stone risk. The mammalian intestine plays a crucial role in oxalate homeostasis, and we had recently reported that

Indexed as

AnimalsCaco-2 CellsCell Line, TumorCyclic AMP-Dependent Protein KinasesEpithelial CellsHumansHyperoxaluriaIntestinal MucosaIntracellular Signaling Peptides and ProteinsIon TransportKidney CalculiOxalatesSignal TransductionCyclic AMP-Dependent Protein KinasesIntracellular Signaling Peptides and ProteinsOxalatesprotein kinase modulatorintestinal oxalate transportPKASLC26A2SLC26A6T84 cells

Identifiers

PMID31825656
PMCPMC7052606
OpenAlexW2994635087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.