ArticleThe British journal of radiology2020
Evaluation of the liver with virtual non-contrast: single institution study in 149 patients undergoing TAVR planning.
Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- The value of virtual non-contrast images derived from dual-energy spectral CT in the short-term efficacy assessment of hepatocellular carcinoma after TACE.European journal of radiology open · 2026Article
- Evaluation of virtual non-contrast detector-based spectral CT images in comparison to true unenhanced images in 20 rabbits.Frontiers in veterinary science · 2025Article
- Virtual Non-Contrast versus True Native in Photon-Counting CT: Stability of Density of Upper Abdominal Organs and Vessels.Diagnostics (Basel, Switzerland) · 2024Article
- Comparison of true non-contrast and virtual non-contrast images in the characterization of renal lesions using detector-based spectral CT.The British journal of radiology · 2023Article
- Principles and Applications of Dual-Layer Spectral CT in Gastrointestinal Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Abdominal virtual non-contrast images derived from energy spectrum CT to evaluate chemotherapy-related fatty liver disease.Quantitative imaging in medicine and surgery · 2023Article
- Detection of fatty liver using virtual non-contrast dual-energy CT.Abdominal radiology (New York) · 2022Article
- Virtual Non-Contrast versus True Non-Contrast Computed Tomography: Initial Experiences with a Photon Counting Scanner Approved for Clinical Use.Diagnostics (Basel, Switzerland) · 2021Article
- Longitudinal reproducibility of attenuation measurements on virtual unenhanced images: multivendor dual-energy CT evaluation.European radiology · 2021Article
- Abdominal vessel depiction on virtual triphasic spectral detector CT: initial clinical experience.Abdominal radiology (New York) · 2021Article
- Quantitative accuracy of virtual non-contrast images derived from spectral detector computed tomography: an abdominal phantom study.Scientific reports · 2020Article
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate accuracy of virtual-non-contrast images (VNC) compared to true-unenhanced-images (TNC) for evaluation of liver attenuation acquired using spectral-detector CT (SDCT).
methods149 patients who underwent multiphase transcatheter-aortic-valve-replacement (TAVR) SDCT-examinations [unenhanced-chest (TNC), CT-angiography chest (CTA-chest, early arterial-phase) and abdomen (CTA-abdomen, additional early arterial-phase after a second injection of contrast media)] were retrospectively included. VNC of CTA-chest (VNC-chest) and CTA-abdomen (VNC-abdomen) were reconstructed and compared to TNC. Region of interest-based measurement of mean attenuation (Hounsfield unit, HU) was applied in the following regions: liver, spleen, abdominal aorta and paraspinal muscle.
resultsVNC accuracy was high in the liver, spleen, abdominal aorta and muscle for abdomen-scanning. For the liver, average attenuation was 59.0 ± 9.1 HU for TNC and 72.6 ± 9.5 HU for CTA-abdomen. Liver attenuation in VNC-abdomen (59.1 ± 6.4 HU) was not significantly different from attenuation in TNC (
conclusionVNC performed well in a large cohort of TAVR-examinations yielding equivalent mean attenuations to TNC; however, application of this technique might be limited when no or very little contrast media is present in parenchyma, more precisely in an early arterial-phase of the liver. ADVANCES IN KNOWLEDGE: This study showed that VNC can be reliably applied in cardiac protocols when certain limitations are considered.
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