Evidence map›Paper›PMID 31825513›Full record

ArticleMolecular biology and evolution2020

A Bayesian Implementation of the Multispecies Coalescent Model with Introgression for Phylogenomic Analysis.

Tomáš Flouri, Xiyun Jiao, Bruce Rannala, Ziheng Yang

Erratum issuedAbstract readEvaluation Study
In one paragraph

Article in Molecular biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Gene tree patterns help answer: vicariance or dispersal?bioRxiv : the preprint server for biology · 2026
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  18. The power of coalescent methods for inferring recent and ancient gene flow in endangered Bactrian camels.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Phylogenetic networks empower biodiversity research.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Tomáš FlouriDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Xiyun JiaoDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Bruce RannalaDepartment of Evolution and Ecology, University of California, Davis, Davis, CA.
Ziheng YangDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/N000609/1Biotechnology and Biological Sciences Research Council BB/P006493/1Biotechnology and Biological Sciences Research Council BB/R01356X/1
6 · The paper itself

Abstract

Recent analyses suggest that cross-species gene flow or introgression is common in nature, especially during species divergences. Genomic sequence data can be used to infer introgression events and to estimate the timing and intensity of introgression, providing an important means to advance our understanding of the role of gene flow in speciation. Here, we implement the multispecies-coalescent-with-introgression model, an extension of the multispecies-coalescent model to incorporate introgression, in our Bayesian Markov chain Monte Carlo program Bpp. The multispecies-coalescent-with-introgression model accommodates deep coalescence (or incomplete lineage sorting) and introgression and provides a natural framework for inference using genomic sequence data. Computer simulation confirms the good statistical properties of the method, although hundreds or thousands of loci are typically needed to estimate introgression probabilities reliably. Reanalysis of data sets from the purple cone spruce confirms the hypothesis of homoploid hybrid speciation. We estimated the introgression probability using the genomic sequence data from six mosquito species in the Anopheles gambiae species complex, which varies considerably across the genome, likely driven by differential selection against introgressed alleles.

Indexed as

Genetic IntrogressionModels, GeneticPhylogenyAnimalsAnophelesBayes TheoremPiceaSaccharomycetalesBayesian inferenceBppintrogressionMCMCMScimultispecies coalescent with introgression

Identifiers

PMID31825513
PMCPMC7086182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.