Observational studyJAMA network open2019
Incidence of, Risk Factors for, and Mortality Associated With Severe Acute Kidney Injury After Gunshot Wound.
Observational study in JAMA network open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07150182 (The Integrated Shared Decision-making Program of Critical Hemodialysis Initiation - the Effects on Decision Conflict, Decision Regret, Anxiety and Depression Among Family Members), which is not on this map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Integrated Shared Decision-making Program of Critical Hemodialysis Initiation - the Effects on Decision Conflict, Decision Regret, Anxiety and Depression Among Family Members
Who cites it
4 citing papers in PubMed, 26 citations in OpenAlex.
- Assessment of urine CCL2 as a potential diagnostic biomarker for acute kidney injury and septic acute kidney injury in intensive care unit patients.Renal failure · 2024Article
- Building an understanding of Ethnic minority people's Service Use Relating to Emergency care for injuries: the BE SURE study protocol.BMJ open · 2023Article
- Development of mortality prediction model in the elderly hospitalized AKI patients.Scientific reports · 2021Article
- Observational
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: Acute kidney injury increases the risk of mortality in hospitalized patients. However, incidence of severe acute kidney injury (SAKI) and its association with mortality in civilians with gunshot wounds (GSWs) is not known. Objective: To determine the incidence of and risk factors associated with SAKI and acute kidney injury requiring dialysis (AKI-D) after GSWs and the association of SAKI and AKI-D with mortality among civilians in the United States. Design, Setting, and Participants: This retrospective cross-sectional study included civilians with GSW reported to the National Trauma Data Bank between July 1, 2010, and June 30, 2015. Torso GSWs were included in study; GSWs to the head were excluded. The data were analyzed between September and November 2018. Exposure: Civilians with GSW. Main Outcomes and Measures: Incidence of SAKI and AKI-D; association of SAKI and AKI-D with mortality. Results: Most of the 64 059 civilian GSWs affected men (57 431 [89.7%]) and racial/ethnic minorities (36 205 [56.5%] African American individuals; 9681 [15.1%] Hispanic individuals). Incidence of SAKI was 2.3% (1450 of 64 059), and incidence of AKI-D was 0.9% (588 of 64 059). On multivariate analysis, SAKI was associated with older age (odds ratio [OR], 1.02; 95% CI, 1.01-1.02; P < .001), male sex (OR, 1.37; 95% CI, 1.12-1.66; P = .002), diabetes (OR, 1.55; 95% CI, 1.20-2.00; P = .001), hypertension (OR, 1.76; 95% CI, 1.46-2.11; P < .001), Glasgow Coma Scale score (OR, 0.98; 95% CI, 0.96-0.99; P = .002), sepsis (OR, 13.83; 95% CI, 11.77-16.24; P < .001), hollow viscus injury (OR, 2.31; 95% CI, 2.05-2.59; P < .001), and injury severity score (OR, 1.02; 95% CI, 1.01-1.02; P < .001); AKI-D was associated with systolic blood pressure (OR, 0.99; 95% CI, 0.99-1.00; P < .001), sepsis (OR, 1.56; 95% CI, 1.18-2.04; P = .001), and injury severity score (OR, 1.01; 95% CI, 1.01-1.02; P = .001). Mortality was significantly higher in patients with AKI-D (167 of 588 patients [28.4%]) compared with patients with SAKI (172 of 862 [20.0%]) and no SAKI or AKI-D (5521 of 62 609 [8.8%]) (P < .001). Mortality was associated with older age (OR, 1.01; 95% CI, 1.01-1.01; P < .001), systolic blood pressure (OR, 0.997; 95% CI, 0.997-0.998; P < .001), Glasgow Coma Scale score (OR, 0.87; 95% CI, 0.87-0.88; P < .001), SAKI (OR, 2.32; 95% CI, 1.93-2.79; P < .001), AKI-D (OR, 1.46; 95% CI, 1.12-1.90; P < .001), hollow viscus injury (OR, 1.87; 95% CI, 1.76-1.98; P < .001), and higher injury severity score (OR, 1.01; 95% CI, 1.01-1.01; P < .001). After matching for variables except SAKI or AKI-D, patients with SAKI were twice as likely to die than patients without SAKI (320 of 1391 [23.0%] vs 158 of 1391 [11.4%]; P < .001). Conclusions and Relevance: In this cross-sectional study, SAKI among civilians who experienced GSWs was associated with mortality.
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