Evidence map›Paper›PMID 31825465›Full record

ReviewJAMA surgery2020

Artificial Intelligence and Surgical Decision-making.

Tyler J Loftus, Patrick J Tighe, Amanda C Filiberto, Philip A Efron, Scott C Brakenridge, Alicia M Mohr, Parisa Rashidi, Gilbert R Upchurch, Azra Bihorac

Abstract readReview
In one paragraph

Review in JAMA surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 249 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
249citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

249 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  13. Artificial Intelligence Scribes in Orthopaedic Surgery: A Narrative Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
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189 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tyler J LoftusDepartment of Surgery, University of Florida Health, Gainesville.
Patrick J TigheDepartments of Anesthesiology, Orthopedics, and Information Systems/Operations Management, University of Florida Health, Gainesville.
Amanda C FilibertoDepartment of Surgery, University of Florida Health, Gainesville.
Philip A EfronDepartment of Surgery, University of Florida Health, Gainesville.
Scott C BrakenridgeDepartment of Surgery, University of Florida Health, Gainesville.
Alicia M MohrDepartment of Surgery, University of Florida Health, Gainesville.
Parisa RashidiDepartments of Biomedical Engineering, Computer and Information Science and Engineering, and Electrical and Computer Engineering, University of Florida, Gainesville.
Gilbert R UpchurchDepartment of Surgery, University of Florida Health, Gainesville.
Azra BihoracDepartment of Medicine, University of Florida Health, Gainesville.

Funding

PICS: A New Horizon for Surgical Critical CareP50GM111152 · NIGMS · UNIVERSITY OF FLORIDA · PI BRUMBACK, BABETTE A. · 2014 to 2018
$10.7M
Integrating data, algorithms and clinical reasoning for surgical risk assessmentR01GM110240 · NIGMS · UNIVERSITY OF FLORIDA · PI BIHORAC, AZRA, RASHIDI, PARISA · 2016 to 2025
$5.1M
Molecular Biology in Burns and TraumaT32GM008721 · NIGMS · UNIVERSITY OF FLORIDA · PI Philip A Efron · 1999 to 2026
$5.0M
Chronic Stress and Anemia Recovery following Major TraumaR01GM105893 · NIGMS · UNIVERSITY OF FLORIDA · PI MOHR, ALICIA M · 2013 to 2021
$3.5M
PRECEDE: PREsurgical Cognitive Evaluation via Digital clockfacEdrawingR01AG055337 · NIA · UNIVERSITY OF FLORIDA · PI CATHERINE E PRICE, Parisa Rashidi · 2017 to 2026
$3.2M
Finding Good TEMporal PostOperative pain Signatures (TEMPOS)R01GM114290 · NIGMS · UNIVERSITY OF FLORIDA · PI TIGHE, PATRICK J · 2015 to 2019
$2.5M
Hematopoietic Stem Cell Dysfunction in the Elderly after Severe InjuryR01GM113945 · NIGMS · UNIVERSITY OF FLORIDA · PI EFRON, PHILIP A · 2015 to 2019
$1.6M
Perioperative Cognitive Anesthesia Network (PeCAN) Program for Alzheimer’s Disease and Related DementiasK07AG066813 · NIA · UNIVERSITY OF FLORIDA · PI PRICE, CATHERINE E · 2020 to 2024
$810k
Autonomous Pain Recognition in Non-Verbal and Critically Ill PatientsR21EB027344 · NIBIB · UNIVERSITY OF FLORIDA · PI RASHIDI, PARISA · 2019 to 2022
$577k
NIA NIH HHS K07 AG066813NIA NIH HHS R01 AG055337NIBIB NIH HHS R21 EB027344NIGMS NIH HHS P50 GM111152NIGMS NIH HHS R01 GM105893NIGMS NIH HHS R01 GM110240NIGMS NIH HHS R01 GM113945NIGMS NIH HHS R01 GM114290NIGMS NIH HHS T32 GM008721
6 · The paper itself

Abstract

Importance: Surgeons make complex, high-stakes decisions under time constraints and uncertainty, with significant effect on patient outcomes. This review describes the weaknesses of traditional clinical decision-support systems and proposes that artificial intelligence should be used to augment surgical decision-making. Observations: Surgical decision-making is dominated by hypothetical-deductive reasoning, individual judgment, and heuristics. These factors can lead to bias, error, and preventable harm. Traditional predictive analytics and clinical decision-support systems are intended to augment surgical decision-making, but their clinical utility is compromised by time-consuming manual data management and suboptimal accuracy. These challenges can be overcome by automated artificial intelligence models fed by livestreaming electronic health record data with mobile device outputs. This approach would require data standardization, advances in model interpretability, careful implementation and monitoring, attention to ethical challenges involving algorithm bias and accountability for errors, and preservation of bedside assessment and human intuition in the decision-making process. Conclusions and Relevance: Integration of artificial intelligence with surgical decision-making has the potential to transform care by augmenting the decision to operate, informed consent process, identification and mitigation of modifiable risk factors, decisions regarding postoperative management, and shared decisions regarding resource use.

Indexed as

Artificial IntelligenceClinical Decision-MakingDecision Support Systems, ClinicalSurgical Procedures, OperativeElectronic Health RecordsEmotionsHumansIntuitionTime FactorsUncertainty

Identifiers

PMID31825465
PMCPMC7286802

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.