Evidence map›Paper›PMID 31825307›Full record

ArticleeLife2019

MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment.

Flavio H Beraldo, Daniel Palmer, Sara Memar, David I Wasserman, Wai-Jane V Lee, Shuai Liang, Samantha D Creighton, Benjamin Kolisnyk, Matthew F Cowan, Justin Mels and 11 more

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Advances and opportunities for computational interrogation of plant proteins.The Plant journal : for cell and molecular biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Flavio H Beraldo *Robarts Research Institute, The University of Western Ontario, Ontario, Canada.ORCID 0000-0001-7638-2007
Daniel Palmer *Robarts Research Institute, The University of Western Ontario, Ontario, Canada.ORCID 0000-0002-3419-8647
Sara Memar *Robarts Research Institute, The University of Western Ontario, Ontario, Canada.
David I Wasserman *Robarts Research Institute, The University of Western Ontario, Ontario, Canada.
Wai-Jane V LeeRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Shuai LiangRotman Research Institute, Baycrest Hospital, Toronto, Canada.
Samantha D CreightonDepartment of Psychology and Neuroscience Program, University of Guelph, Guelph, Canada.
Benjamin KolisnykRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Matthew F CowanRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Justin MelsRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Talal S MasoodRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Chris FodorRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Mohammed A Al-OnaiziRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Robert BarthaRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Tom GeeRotman Research Institute, Baycrest Hospital, Toronto, Canada.
Lisa M SaksidaRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Timothy J BusseyRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Stephen S StrotherRotman Research Institute, Baycrest Hospital, Toronto, Canada.ORCID 0000-0002-3198-217X
Vania F PradoRobarts Research Institute, The University of Western Ontario, Ontario, Canada.
Boyer D WintersDepartment of Psychology and Neuroscience Program, University of Guelph, Guelph, Canada.ORCID 0000-0003-3613-4441
Marco Am PradoRobarts Research Institute, The University of Western Ontario, Ontario, Canada.ORCID 0000-0002-3028-5778

Funding

Brain Canada Canada Open Neuroscience PlatformBrain Canada Multi-Investigator Research GrantCanada First Research Excellence Fund BrainsCANCIHR MOP126000CIHR MOP136930CIHR MOP89919
6 · The paper itself

Abstract

Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the availability of tools to share and disseminate data is scarce. Automated touchscreen-based tests enable systematic cognitive assessment with easily standardised outputs that can facilitate data dissemination. Here we present an integration of touchscreen cognitive testing with an open-access database public repository (mousebytes.ca), as well as a Web platform for knowledge dissemination (https://touchscreencognition.org). We complement these resources with the largest dataset of age-dependent high-level cognitive assessment of mouse models of Alzheimer's disease, expanding knowledge of affected cognitive domains from male and female mice of three strains. We envision that these new platforms will enhance sharing of protocols, data availability and transparency, allowing meta-analysis and reuse of mouse cognitive data to increase the replicability/reproducibility of datasets.

Indexed as

RodentiaAlzheimer DiseaseAnimalsBehavior, AnimalChoice BehaviorCognitionDatabases, FactualDisease Models, AnimalFemaleLaboratory Animal ScienceLearningMaleMemoryMiceNeuropsychological TestsReproducibility of ResultsAlzheimer's diseaseamyloid-beta plaquescognitionhigh-throughput screeningmouseneuroscienceopen-access databasetouchscreen

Identifiers

PMID31825307
PMCPMC6934379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.