Evidence map›Paper›PMID 31824826›Full record

ArticleTissue engineering and regenerative medicine2019

Bladder Augmentation Using Lyoplant

F Winde, K Backhaus, J A Zeitler, N Schlegel, Th Meyer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering and regenerative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

F Winde1Pediatric Surgery-, Pediatric Trauma - and Pediatric Urology Unit, Department of General-, Visceral-, Transplant-, Vascular- and Pediatric Surgery, University Hospital Wuerzburg, Würzburg, Germany.
K Backhaus1Pediatric Surgery-, Pediatric Trauma - and Pediatric Urology Unit, Department of General-, Visceral-, Transplant-, Vascular- and Pediatric Surgery, University Hospital Wuerzburg, Würzburg, Germany.
J A Zeitler2Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.
N Schlegel3Experimental Surgery Unit, Department of General-, Visceral-, Transplant-, Vascular- and Pediatric Surgery, University of Wuerzburg, Würzburg, Germany.
Th Meyer1Pediatric Surgery-, Pediatric Trauma - and Pediatric Urology Unit, Department of General-, Visceral-, Transplant-, Vascular- and Pediatric Surgery, University Hospital Wuerzburg, Würzburg, Germany.
Universitätsklinikum Würzburg · DEUniversity of Cambridge · GBUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Congenital defects of the urinary bladder (micro- or contracted bladder, bladder exstrophy) remain a challenging problem for pediatric surgeons. Even when conservative treatment options are fully exhausted, irreversible renal dysfunction can be observed in a large number of cases that can even lead to chronic renal failure and the need for kidney transplantation. To protect kidney function bladder augmentation using intestinal tissue is commonly applied as the standard treatment method. However due to the unphysiological nature of intestinal tissue a number of problems and complications such as urinary tract infections or bladder stone formation limit the clinical success of this approach. Moreover a number of substitutes for the implementation of a bladder augmentation have been tested without success to date. Here we used an experimental model to test wether the biocompatible collagen mesh Lyoplant may be a suitable candidate for bladder augmentation. Methods: We implanted a biocompatible collagen mesh (Lyoplant Results: All but one rat exhibited physiological growth and behaviour after the operation without differences between the Lyoplant Conclusion: In summary, Lyoplant

Indexed as

AnimalsBiocompatible MaterialsCollagenProstheses and ImplantsRatsRats, WistarRegenerationTh2 CellsUrinary BladderWound HealingBiocompatible MaterialsCollagenBiocompatible collagen meshBladder regeneration/augmentationRat model

Identifiers

PMID31824826
PMCPMC6879694
OpenAlexW2980450427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.