Evidence map›Paper›PMID 31824672›Full record

ArticleF1000Research2019

Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza.

Zhiping Yang, Alice Bedugnis, Susan Levinson, Mark DiNubile, Thomas Stossel, Quan Lu, Lester Kobzik

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhiping YangDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Alice BedugnisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Susan LevinsonBioAegis Therapeutics, North Brunswick, NJ, 07960, USA.
Mark DiNubileBioAegis Therapeutics, North Brunswick, NJ, 07960, USA.
Thomas StosselBioAegis Therapeutics, North Brunswick, NJ, 07960, USA.
Quan LuDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Lester KobzikDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.ORCID 0000-0003-4328-937X
Harvard University · US

Funding

Plasma Gelsolin as Immunotherapeutic for Antibiotic-Resistant PneumoniaR01AI125152 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI LU, QUAN · 2016 to 2018
$2.8M
NIAID NIH HHS R01 AI125152
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GelsolinInfluenza, HumanRecombinant ProteinsAnimalsDisease Models, AnimalHumansInflammationMiceSurvival AnalysisGelsolinRecombinant Proteinshost-directedimmunomodulationinfluenzaplasma gelsolinpneumonia

Identifiers

PMID31824672
PMCPMC6894358
OpenAlexW2984009543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.