Evidence map›Paper›PMID 31824659›Full record

ReviewF1000Research2019

Recent advances in understanding and managing malabsorption: focus on microvillus inclusion disease.

Dulari Jayawardena, Waddah A Alrefai, Pradeep K Dudeja, Ravinder K Gill

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Three patients with new mutations in theTranslational pediatrics · 2024
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  14. New mutation inWorld journal of clinical cases · 2020
    Article
  15. The Endosomal Recycling Pathway-At the Crossroads of the Cell.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dulari JayawardenaDivision of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Waddah A AlrefaiDivision of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Pradeep K DudejaDivision of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Ravinder K GillDivision of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
University of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microvillus inclusion disease (MVID) is a rare congenital severe malabsorptive and secretory diarrheal disease characterized by blunted or absent microvilli with accumulation of secretory granules and inclusion bodies in enterocytes. The typical clinical presentation of the disease is severe chronic diarrhea that rapidly leads to dehydration and metabolic acidosis. Despite significant advances in our understanding of the causative factors, to date, no curative therapy for MVID and associated diarrhea exists. Prognosis mainly relies on life-long total parenteral nutrition (TPN) and eventual small bowel and/or liver transplantation. Both TPN and intestinal transplantation are challenging and present with many side effects. A breakthrough in the understanding of MVID emanated from seminal findings revealing mutations in

Indexed as

Malabsorption SyndromesMucolipidosesAnimalsHumansMicrovilliMyosin Heavy ChainsMyosin Type VMyosin Heavy ChainsMyosin Type Vdiarrheaepithelial transportmalabsorptionMVIDtrafficking

Identifiers

PMID31824659
PMCPMC6896243
OpenAlexW2993538165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.