Evidence map›Paper›PMID 31824633›Full record

ReviewFacts, views & vision in ObGyn2019

Experiences of a multistep process with medical and psychological interventions for patients with congenital uterine aplasia to achieve motherhood: the Gothenburg-Tübingen collaboration.

S Y Brucker, F-A Taran, K Rall, D Schöller, P Dahm-Kâhler, N Kvarnström, S Järvholm, S Nadalin, A Königsrainer, D Wallwiener and 1 more

Abstract readReview
In one paragraph

Review in Facts, views & vision in ObGyn, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S Y BruckerDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
F-A TaranDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
K RallDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
D SchöllerDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
P Dahm-KâhlerDepartment of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
N KvarnströmDepartment of Transplantation, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
S JärvholmDepartment of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
S NadalinDepartment of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany.
A KönigsrainerDepartment of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany.
D WallwienerDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
M BrännströmDepartment of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital uterine aplasia, also known as Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a condition associated to a non-functional uterus in the presence of functional ovaries. In a setting where surrogacy is illegal (or not accepted) and adoption is the only alternative, neovaginoplasty and subsequent uterus transplantation (UTx) can provide a route to motherhood for women with MRKHS. This review article describes a multistep process by which patients with MRKHS can achieve motherhood with their own biological child. This process involving a careful clinical diagnosis, psychological counselling, assessment of eligibility for neovagina creation and UTx, the surgical treatment, fertility treatment, and long-term follow-up was developed at the Tübingen University Hospital and in close collaboration with Sahlgrenska Academy, University of Gothenburg, Sweden, where the basic experimental and clinical groundwork for UTx was laid and the first-ever UTx procedure was performed.

Indexed as

congenital uterine and vaginal aplasialaparoscopic-assisted neovaginaMRKH-Syndromeuterus transplantationVecchietti

Identifiers

PMID31824633
PMCPMC6897517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.