Evidence map›Paper›PMID 31824594›Full record

ArticleJournal of clinical and experimental dentistry2019

Gingival hyperplasia as an early manifestation of acute myeloid leukemia. A retrospective review.

Nansi López-Valverde, Antonio López-Valverde, Rafael Gómez-de Diego, Juan M Ramírez, Javier Flores-Fraile, Jorge Muriel-Fernández

Abstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Oral manifestations of leukemia as part of early diagnosis.Hematology, transfusion and cell therapy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nansi López-ValverdeDepartment of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Antonio López-ValverdeDepartment of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Rafael Gómez-de DiegoDepartment of Oral Medicine. Rey Juan Carlos University, Madrid, Spain.
Juan M RamírezDepartment of Morphological Sciences. University of Cordoba, Cordoba, Spain.
Javier Flores-FraileDepartment of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Jorge Muriel-FernándezDepartment of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe study the prevalence of acute myeloid leukemia (AML) among patients with severe gingival enlargement. MATERIAL AND

methodsWe retrospective reviewed the clinical records of patients with severe gingival enlargement, between 2011 and 2018. The Saxer and Mühlemann index were used to measure inflammation and gingival bleeding. The degree of dental mobility was measured by the Nyman and Lindhe technique.

resultsA correlation analysis was carried out to test whether there were any associations among the different variables. In the sample of 117 patients the mean gingival bleeding index was ≥3 and the degree of dental mobility ≥2.3. 1.7% of patients, with severe gingival hyperplasia were diagnosed with AML. We found a significant association between gingival bleeding and aging (

conclusionsSevere gingival enlargement, abundant gingival bleeding, and dental mobility could be early manifestations of a blood dyscrasia.

Identifiers

PMID31824594
PMCPMC6894908

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