ReviewFrontiers in microbiology2019
Fungal Cell Wall: Emerging Antifungals and Drug Resistance.
Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 206 citations in OpenAlex.
- Fosmanogepix: A comprehensive review of its origin, mechanism, antifungal efficacy, and resistance (Review).Biomedical reports · 2026Review
- Comparative transcriptome and proteome analysis of resistant and susceptibleAntimicrobial agents and chemotherapy · 2026Article
- Miltefosine regulates gene expression related to morphogenesis and zinc metabolism inMicrobiology spectrum · 2026Article
- Antifungal activity and potential mechanisms of two new bafilomycin analogues from Streptomyces sp. TH30 against tomato early blight.Pest management science · 2026Article
- Coumarin application modulates antioxidant defense to enhance resistance against Fusarium in mung bean.Scientific reports · 2026Article
- The Structure, Biosynthesis, and Function of β-1,6-Glucan in the Fungal Cell Wall.Biomolecules · 2026Review
- A geometric and probabilistic framework for mechanistic antifungal screening from colony morphology.Pest management science · 2026Article
- In Vitro Anti-Journal of fungi (Basel, Switzerland) · 2026Article
- Bacterial nanocellulose-based encapsulation of Trichoderma harzianum spores for sustainable delivery of fungal biocontrol agents in agriculture.World journal of microbiology & biotechnology · 2026Article
- The Four Critical Priority Fungi According to the World Health Organization and the Hope for New Therapies: A Focus on Cell Wall Antifungal Targets.Journal of fungi (Basel, Switzerland) · 2026Review
- Caspofungin Reshapes the Extracellular Vesicles Metabolome ofJournal of fungi (Basel, Switzerland) · 2026Article
- Inhibition mechanism of the fungal β-1,3-glucan synthases by triterpenoid antifungal drugs.Nature communications · 2026Article
- Antifungal Potential ofJournal of fungi (Basel, Switzerland) · 2026Article
- Schiff base metal complexes as emerging therapeutics against antimicrobial-resistant skin pathogens.ADMET & DMPK · 2026Review
- Interconnected worlds: a comprehensive review of fungal defenses, antimicrobial resistance, and their evolutionary dynamics.IMA fungus · 2026Review
- Antimicrobial activity and antifungal mechanistic study of 3‑substituted oxindoles against Aspergillus niger.Scientific reports · 2025Article
- Influence of Hyptis suaveolens growth stage on essential oil composition, antimicrobial and antioxidant activities.Scientific reports · 2025Article
- Orange Peel-Mediated Green Synthesis of ZnO and CuO Nanoparticles: Evaluation for Antimicrobial Activity and Biocompatibility in Tissue Engineering.International journal of molecular sciences · 2025Article
- Transcription Factor MaHMG, the High-Mobility Group Protein, Is Implicated in Conidiation Pattern Shift and Stress Tolerance inJournal of fungi (Basel, Switzerland) · 2025Article
- The pre-mRNA splicing modulator pladienolide B inhibitsmSphere · 2025Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in human cells makes this component an attractive target for antifungal development. The host environment and antifungal stress can lead to cell wall modifications related to drug resistance. Antifungals targeting the cell wall including the new β-D-glucan synthase inhibitor ibrexafungerp and glycosyl-phosphatidyl Inositol (GPI) anchor pathway inhibitor fosmanogepix are promising weapons against antifungal resistance. The fosmanogepix shows strong
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.