Evidence map›Paper›PMID 31824335›Full record

ArticleFrontiers in physiology2019

Attenuation Correction Approaches for Serotonin Transporter Quantification With PET/MRI.

Lucas Rischka, Gregor Gryglewski, Neydher Berroterán-Infante, Ivo Rausch, Gregory Miles James, Manfred Klöbl, Helen Sigurdardottir, Markus Hartenbach, Andreas Hahn, Wolfgang Wadsak and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Lucas RischkaDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Gregor GryglewskiDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Neydher Berroterán-InfanteDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Ivo RauschQIMP Group, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Gregory Miles JamesDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Manfred KlöblDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Helen SigurdardottirDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Markus HartenbachDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Andreas HahnDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Wolfgang WadsakDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Markus MitterhauserDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Thomas BeyerQIMP Group, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Siegfried KasperDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Daniela PrayerDivision of Neuroradiology and Musculoskeletal Radiology, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Marcus HackerDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATCenter For Biomarker Research In Medicine · ATLudwig Boltzmann Institute Applied Diagnostics · AT

Funding

Austrian Science Fund FWF KLI 516
6 · The paper itself

Abstract

backgroundSeveral MR-based attenuation correction (AC) approaches were developed to conquer the challenging AC in hybrid PET/MR imaging. These AC methods are commonly evaluated on standardized uptake values or tissue concentration. However, in neurotransmitter system studies absolute quantification is more favorable due to its accuracy. Therefore, our aim was to investigate the accuracy of segmentation- and atlas-based MR AC approaches on serotonin transporter (SERT) distribution volumes and occupancy after a drug challenge.

methods18 healthy subjects (7 male) underwent two [

resultsVariations for V

conclusionThe high correlation might offer a rescaling from the biased parameters V

Indexed as

[11C]DASBabsolute quantificationattenuation correctionoccupancyPET/MRIserotonin transporter

Identifiers

PMID31824335
PMCPMC6883225
OpenAlexW2990480249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.