Evidence map›Paper›PMID 31824294›Full record

ArticleFrontiers in aging neuroscience2019

Lagged Coupled Changes Between White Matter Microstructure and Processing Speed in Healthy Aging: A Longitudinal Investigation.

Jessica Oschwald, Susan Mérillat, Franziskus Liem, Christina Röcke, Mike Martin, Lutz Jäncke

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica OschwaldUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Susan MérillatUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Franziskus LiemUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Christina RöckeUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Mike MartinUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Lutz JänckeUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related differences in white matter (WM) microstructure have been linked to lower performance in tasks of processing speed in healthy older individuals. However, only few studies have examined this link in a longitudinal setting. These investigations have been limited to the correlation of simultaneous changes in WM microstructure and processing speed. Still little is known about the nature of age-related changes in WM microstructure, i.e., regionally distinct vs. global changes. In the present study, we addressed these open questions by exploring whether previous changes in WM microstructure were related to subsequent changes in processing speed: (a) 1 year later; or (b) 2 years later. Furthermore, we investigated whether age-related changes in WM microstructure were regionally specific or global. We used data from four occasions (covering 4 years) of the Longitudinal Healthy Aging Brain (LHAB) database project (

Indexed as

coupled changesfractional anisotropyhealthy aginglatent change score modellongitudinalprocessing speedstructural equation modeling (SEM)white matter microstructure

Identifiers

PMID31824294
PMCPMC6881240

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.