Evidence map›Paper›PMID 31824265›Full record

ArticleFrontiers in cellular neuroscience2019

Otoprotection to Implanted Cochlea Exposed to Noise Trauma With Dexamethasone Eluting Electrode.

Adrien A Eshraghi, Amit Wolfovitz, Rasim Yilmazer, Carolyn Garnham, Ayca Baskadem Yilmazer, Esperanza Bas, Peter Ashman, Jonathan Roell, Jorge Bohorquez, Rahul Mittal and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. An Experimental Study on the Protective Effect of Memantine in Noise-Induced Hearing Loss.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  2. Article
  3. Review
  4. Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Evolution of drug-eluting biomedical implants for sustained drug delivery.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Adrien A EshraghiDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Amit WolfovitzDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Rasim YilmazerDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Carolyn GarnhamMED-EL Hearing Implants, Innsbruck, Austria.
Ayca Baskadem YilmazerDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Esperanza BasDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Peter AshmanDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Jonathan RoellDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Jorge BohorquezDepartment of Biomedical Engineering, University of Miami, Miami, Coral Gables, FL, United States.
Rahul MittalDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
Roland HesslerMED-EL Hearing Implants, Innsbruck, Austria.
Daniel SieberMED-EL Hearing Implants, Innsbruck, Austria.
Jeenu MittalDepartment of Otolaryngology, University of Miami Hearing Research Laboratory, Miller School of Medicine, Miami, FL, United States.
University of Miami · USMED-EL (Austria) · ATNeurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cochlear implantation (CI) is now widely used to provide auditory rehabilitation to individuals having severe to profound sensorineural hearing loss (SNHL). However, CI can lead to electrode insertion trauma (EIT) that can cause damage to sensory cells in the inner ear resulting in loss of residual hearing. Even with soft surgical techniques where there is minimal macroscopic damage, we can still observe the generation of molecular events that may initiate programmed cell death

Indexed as

cochlear implantationdexamethasonedrug-eluting electrodeshearing losslocal drug deliverynoise traumaotoprotection

Identifiers

PMID31824265
PMCPMC6882736
OpenAlexW2981896889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.