Evidence map›Paper›PMID 31824239›Full record

ArticleFrontiers in neuroscience2019

Analysis of the Gut Microflora in Patients With Parkinson's Disease.

Miao Jin, Jing Li, Fei Liu, Na Lyu, Kang Wang, Lu Wang, Shihao Liang, Hua Tao, Baoli Zhu, Rashad Alkasir

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. The microbiota-gut-brain axis: a potential target in the small-molecule compounds and gene therapeutic strategies for Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miao JinNeurology Department of China - Japan Friendship Hospital, Beijing, China.
Jing LiInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Fei LiuInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Na LyuInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Kang WangNeurology Department of China - Japan Friendship Hospital, Beijing, China.
Lu WangNeurology Department of China - Japan Friendship Hospital, Beijing, China.
Shihao LiangInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Hua TaoInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Baoli ZhuInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Rashad AlkasirInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to explore the composition of the fecal microflora of Chinese Parkinson's disease (PD) patients, as well as to explore links between PD clinical features and antiparkinsonian medications on the gut microflora. Seventy-two PD cases [59 patients suffering from PD for >1 year (OPD) and 13 new PD (NPD) patients] were studied. Microflora communities in the feces of the patients and corresponding healthy controls (HCs) were examined using high-throughput Illumina MiSeq sequencing targeting the 16S rRNA gene. The gut microflora of OPD patients contained high levels of Rikenellaceae compared to corresponding HCs. In addition, significantly higher levels of Turicibacteraceae were found in the NPD group compared to the corresponding HCs. The genera

Indexed as

16S rRNA genegut microfloraIllumina MiSeqParkinson's diseasePrevotellaTuricibacter

Identifiers

PMID31824239
PMCPMC6883725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.