Evidence map›Paper›PMID 31823884›Full record

ArticleNeural regeneration research2020

Modified constraint-induced movement therapy alters synaptic plasticity of rat contralateral hippocampus following middle cerebral artery occlusion.

Bei-Yao Gao, Dong-Sheng Xu, Pei-Le Liu, Ce Li, Liang Du, Yan Hua, Jian Hu, Jia-Yun Hou, Yu-Long Bai

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. LongitudinalTheranostics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bei-Yao GaoDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Dong-Sheng XuRehabilitation Section, Department of Spine Surgery, Tongji Hospital of Tongji University; Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of Education, Shanghai, China.
Pei-Le LiuDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Ce LiDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Liang DuDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Yan HuaDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jian HuDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jia-Yun HouZhongshan Hospital Institute of Clinical Science, Fudan University, Shanghai, China.
Yu-Long BaiDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CNTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modified constraint-induced movement therapy is an effective treatment for neurological and motor impairments in patients with stroke by increasing the use of their affected limb and limiting the contralateral limb. However, the molecular mechanism underlying its efficacy remains unclear. In this study, a middle cerebral artery occlusion (MCAO) rat model was produced by the suture method. Rats received modified constraint-induced movement therapy 1 hour a day for 14 consecutive days, starting from the 7

Indexed as

brain-derived neurotrophic factorglutamatehippocampusmCIMTmiddle cerebral artery occlusionmodified constraint-induced movement therapyα-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor

Identifiers

PMID31823884
PMCPMC7034265
OpenAlexW2995654508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.