Evidence map›Paper›PMID 31823875›Full record

ReviewNeural regeneration research2020

The extended renin-angiotensin system: a promising target for traumatic brain injury therapeutics.

Zachary C Janatpour, Aviva J Symes

Registry-linked trialAbstract readReview
In one paragraph

Review in Neural regeneration research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06282965 (A Randomized, Double-blind, Placebo Controlled Study of the Safety and Efficacy of Angiotensin), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06282965 phase1 / phase2recruitingnot on this mapstarted 2024, after this paper: background citation

A Randomized, Double-blind, Placebo Controlled Study of the Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (TBI)

TypeinterventionalSponsorUniversity of ArizonaRan2024 to 2027Enrolled90ConditionsTraumatic Brain InjuryArmsAngiotensin (1-7), Sterile saline
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. The Renin Angiotensin System as a Therapeutic Target in Traumatic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  3. The Angiotensin ATPharmacological reviews · 2022
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zachary C JanatpourDepartment of Pharmacology, Uniformed Services University, Bethesda, MD, USA.
Aviva J SymesDepartment of Pharmacology, Uniformed Services University, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID31823875
PMCPMC7034274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.