Evidence map›Paper›PMID 31823825›Full record

ArticleStem cell research & therapy2019

Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling.

Yuanyuan Kong, Xiaoli Hu, Yingqun Zhong, Ke Xu, Buling Wu, Jianmao Zheng

Open access · goldAbstract read
In one paragraph

Article in Stem cell research & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. International journal of molecular sciences · 2025
    Article
  7. Article
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  9. Article
  10. Article
  11. Article
  12. Application of anFrontiers in cellular neuroscience · 2024
    Article
  13. Article
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  16. SrFeMaterials today. Bio · 2022
    Article
  17. Review
  18. Influencing factors of pulp-dentin complex regeneration and related biological strategies.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuanyuan KongDepartment of Stomatology, Nanfang Hospital, College of Stomatology, Southern Medical University, Guangzhou, 510055, China.
Xiaoli HuGuangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.
Yingqun ZhongGuangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.
Ke XuGuangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.
Buling WuDepartment of Stomatology, Nanfang Hospital, College of Stomatology, Southern Medical University, Guangzhou, 510055, China. bulingwu@smu.edu.cn.
Jianmao ZhengGuangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China. zhengjm25@mail.sysu.edu.cn.ORCID 0000-0002-8667-4203
Sun Yat-sen University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnesium (Mg

methodsDPSCs underwent culture in odontogenic medium with the addition of 0, 1, 5, or 10 mM MgCl

resultsMg

conclusionsMg

Indexed as

Bone Morphogenetic Protein 2Cell DifferentiationCell ProliferationDental PulpExtracellular Signal-Regulated MAP KinasesHumansMagnesiumOdontogenesisSignal TransductionSmad ProteinsStem CellsTranscriptomeBone Morphogenetic Protein 2Extracellular Signal-Regulated MAP KinasesMagnesiumSmad ProteinsBMP2DPSCERKMagnesium-enriched microenvironmentOdontogenic differentiation

Identifiers

PMID31823825
PMCPMC6902488
OpenAlexW2996066668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.