ArticleBMC ophthalmology2019
Repeatability of ocular surface vessel density measurements with optical coherence tomography angiography.
Article in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Circumferential multi-contrast mapping of the aqueous outflow pathway in human eyes facilitated by circular-scan optical coherence tomography angiography.Biomedical optics express · 2026Article
- Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025Review
- Conjunctival and retinal microvascular loss in systemic lupus erythematosus: a swept-source OCTA study.Journal of translational medicine · 2025Article
- Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface.Medicina (Kaunas, Lithuania) · 2024Review
- Current clinical applications of anterior segment optical coherence tomography angiography: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Review
- Optical Coherence Tomography Angiography for Evaluation of Conjunctival Vessels in Dry Eyes.Journal of ophthalmology · 2023Article
- Automated Image Threshold Method Comparison for Conjunctival Vessel Quantification on Optical Coherence Tomography Angiography.Translational vision science & technology · 2022Article
- Progress of Bulbar Conjunctival Microcirculation Alterations in the Diagnosis of Ocular Diseases.Disease markers · 2022Review
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Authors and funding
3 authors.
Funding
Abstract
backgroundTo determine the repeatability of measurements of ocular surface vessel density in normal and diseased eyes using optical coherence tomography angiography (OCTA).
methodsTen normal eyes, 10 pinguecula eyes, and 10 pterygium eyes of 30 volunteers were subjected to OCTA (AngioVue Imaging System, Optovue, Inc.). For scanning, we used the corneal adapter module. Each eye was scanned three times in the nasal and temporal directions, separately. AngioVue software was used to generate the ocular surface vessel density. Ocular surface vessel density was defined as the proportion of vessel area with blood flow to the total measurement area (3 × 3 mm
resultsThe CVs were less than 5% in all subjects, and the ICCs exceeded 0.9; thus, all measurements showed good repeatability. The nasal vessels densities differed significantly between healthy eyes and eyes with pterygium (P < 0.05); however, there was no significant difference between healthy eyes and eyes with pinguecula (P = 0.466).
conclusionsThese results suggest that measurement of ocular surface vessel density by OCTA in normal eyes and eyes with pterygium and pinguecula is repeatable. This preliminary research describes a quantitative and visual method for assessing vessel density of the ocular surface with a high level of consistency.
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