Evidence map›Paper›PMID 31823674›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Renal hemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep under total intravenous anesthesia.

Roger G Evans, Naoya Iguchi, Andrew D Cochrane, Bruno Marino, Sally G Hood, Rinaldo Bellomo, Peter R McCall, Clive N May, Yugeesh R Lankadeva

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Observational
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  4. Review
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  9. MRI of kidney size matters.Magma (New York, N.Y.) · 2024
    Review
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  12. Article
  13. Article
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  16. American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  17. Looking Back on Seven Years ofAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Roger G EvansCardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-9241-0757
Naoya IguchiPre-Clinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia.
Andrew D CochraneDepartment of Cardiothoracic Surgery, Monash Health and Department of Surgery (School of Clinical Sciences at Monash Health), Monash University, Melbourne, Victoria, Australia.
Bruno MarinoCellsaving and Perfusion Resources, Melbourne, Victoria, Australia.
Sally G HoodPre-Clinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia.
Rinaldo BellomoDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australia.
Peter R McCallDepartment of Anesthesia, Austin Health, Heidelberg, Victoria, Australia.
Clive N MayPre-Clinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-8548-3846
Yugeesh R LankadevaPre-Clinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-3589-9111
The University of Melbourne · AUAustin Health · AUAustralian Regenerative Medicine Institute · AUMonash Health · AUStem Cells Australia · AU

Funding

Neurovascular Regulation During Exercise In Humans With Chronic Kidney DiseaseR01HL135183 · NHLBI · EMORY UNIVERSITY · PI Jeanie Park · 2017 to 2026
$5.4M
Sympatho-inhibition with Mindfulness in Chronic Kidney DiseaseR61AT010457 · NCCIH · EMORY UNIVERSITY · PI PARK, JEANIE · 2019 to 2020
$946k
NCCIH NIH HHS R61 AT010457NHLBI NIH HHS R01 HL135183
6 · The paper itself

Abstract

Renal medullary hypoxia may contribute to the pathophysiology of acute kidney injury, including that associated with cardiac surgery requiring cardiopulmonary bypass (CPB). When performed under volatile (isoflurane) anesthesia in sheep, CPB causes renal medullary hypoxia. There is evidence that total intravenous anesthesia (TIVA) may preserve renal perfusion and renal oxygen delivery better than volatile anesthesia. Therefore, we assessed the effects of CPB on renal perfusion and oxygenation in sheep under propofol/fentanyl-based TIVA. Sheep (

Indexed as

Anesthesia, IntravenousHemodynamicsRenal CirculationAcute Kidney InjuryAnesthetics, IntravenousAnimalsBiomarkersCardiopulmonary BypassFentanylHypoxiaKidney MedullaModels, AnimalOxygenPropofolProtective FactorsRisk FactorsAnesthetics, IntravenousBiomarkersFentanylOxygenPropofolacute kidney injurycardiac surgeryhypoxiarenal circulation

Identifiers

PMID31823674
PMCPMC7199239
OpenAlexW2996648760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.