ReviewBritish journal of clinical pharmacology2020
Sustaining and spreading penicillin allergy delabelling: A narrative review of the challenges for service delivery and patient safety.
Review in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Sustaining accurate penicillin allergy labels through electronic health record interoperability: a cross-sectional observational follow-up study 3 years after initial penicillin allergy evaluation.BMJ open quality · 2026Article
- Diagnostic Communication and the Care That Follows: A Critical Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Penicillin Allergy, Really?-A Cross-Sectional Mixed-Methods Study in Baden-Württemberg, Germany, to Explore General Practitioner Perspectives on Delabeling Potential in Primary Care.Antibiotics (Basel, Switzerland) · 2026Article
- What are patients' and healthcare professionals' views on managing penicillin allergy? A qualitative evidence synthesis.JAC-antimicrobial resistance · 2026Review
- Documentation of Drug and Non-Drug Allergies in Public Hospital Electronic Health Records: A National Survey.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Article
- Patients' acceptance of a penicillin allergy de-labelling programme in primary care: a qualitative study.BJGP open · 2025Article
- Antepartum vs postpartum amoxicillin oral challenge in pregnant patients with a reported penicillin allergy: A two-center prospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Factors influencing implementation and adoption of direct oral penicillin challenge for allergy delabelling: a qualitative evaluation.BMJ open quality · 2024Article
- Barriers to and Facilitators of Delabelling of Antimicrobial Allergies: A Qualitative Meta-synthesis.The Canadian journal of hospital pharmacy · 2024Review
- A new pathway for penicillin delabeling in Norway.The World Allergy Organization journal · 2023Article
- Penicillin de-labelling in vancouver, British Columbia, Canada: comparison of approaches, outcomes and future directions.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Safety Aspects and Rational Use of Single Intramuscular Dose Ceftriaxone: Clinical Insights on the Management of Uncomplicated Gonococcal Infections.Drug, healthcare and patient safety · 2023Review
- Patients with questionable penicillin (beta-lactam) allergy: Causes and solutions.Allergologie select · 2022Review
- Management of penicillin allergy in primary care: a qualitative study with patients and primary care physicians.BMC family practice · 2021Article
- The role of a clinical pharmacist in spurious Penicillin allergy: a narrative review.International journal of clinical pharmacy · 2021Review
- Genome-wide Study Identifies Association between HLA-BAmerican journal of human genetics · 2020Article
- Sustaining and spreading penicillin allergy delabelling: A narrative review of the challenges for service delivery and patient safety.British journal of clinical pharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many patients report allergies to penicillin, although in over 90% of these the label of penicillin allergy is shown to be incorrect following comprehensive testing. Inappropriate and inaccurate penicillin allergy labelling is a barrier to antimicrobial stewardship and can lead to patient harm. This review assesses an emergent evidence base and trend favouring delabelling using direct oral penicillin challenges following a stratified risk assessment of the likelihood and existence of true penicillin allergy, to identify and make recommendations for key components for implementation in standard practice. Research to date has focussed on the feasibility and clinical and financial outcomes of these direct delabelling strategies. There is a paucity of studies exploring the views and engagement of patients and healthcare professionals, and a gap in the evidence for prerequisites to safely deliver, sustain and spread the implementation of such services across health systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.