ArticleLa Radiologia medica2020
Minor components of micropapillary and solid subtypes in lung invasive adenocarcinoma (≤ 3 cm): PET/CT findings and correlations with lymph node metastasis.
Article in La Radiologia medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 54 citations in OpenAlex.
- A retrospective cohort study integrating invasive mucinous adenocarcinoma into the IASLC grading system for lung adenocarcinoma.Translational lung cancer research · 2026Article
- Nonlinear association between standardized uptake value (SUV) index based onQuantitative imaging in medicine and surgery · 2026Article
- Novel insights into predicting the presence of micropapillary and solid components in stage IA lung adenocarcinoma using machine learning models of modifiable risk factors.Annals of medicine · 2025Article
- Development and validation of a computed tomography-based radiomics-clinical model to preoperatively predict high-grade patterns within lung invasive adenocarcinoma.Journal of thoracic disease · 2025Article
- 2.5D deep learning radiomics and clinical data for predicting occult lymph node metastasis in lung adenocarcinoma.BMC medical imaging · 2025Article
- The Solid Volume Ratio is Better Than the Consolidation Tumor Ratio in Predicting the Malignant Pathological Features of cT1 Lung Adenocarcinoma.The Thoracic and cardiovascular surgeon · 2025Article
- Article
- Application and progress of non-invasive imaging in predicting lung invasive non-mucinous adenocarcinoma under the new IASLC grading guidelines.Insights into imaging · 2025Review
- Prediction of lymph node metastasis in lung adenocarcinoma using a PET/CT radiomics-based ensemble learning model and its pathological basis.Frontiers in oncology · 2025Article
- Predicting prognosis in patients with stage IA lung adenocarcinoma with a micropapillary component using a nomogram based on computed tomography radiomics and clinicopathologic factors: a retrospective analysis.Translational lung cancer research · 2024Article
- Sublobar resection for lung adenocarcinoma less than 2 cm containing solid or micropapillary components radiologically presented as consolidation-to-tumor ratio (CTR) ≤0.25 [ground-glass opacity (GGO)].Translational lung cancer research · 2024Article
- Feasibility of UTE-MRI-based radiomics model for prediction of histopathologic subtype of lung adenocarcinoma: in comparison with CT-based radiomics model.European radiology · 2024Article
- Accurate categorization and rapid pathological diagnosis correction with Micro-Raman technique in human lung adenocarcinoma infiltration level.Translational lung cancer research · 2024Article
- Development and validation of a clinic-radiological model to predict tumor spread through air spaces in stage I lung adenocarcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Predictive value of systemic immune-inflammation index in the high-grade subtypes components of small-sized lung adenocarcinoma.Journal of cardiothoracic surgery · 2024Article
- Impact of lung adenocarcinoma subtypes on survival and timing of brain metastases.Frontiers in oncology · 2024Article
- Predicting lymph node metastasis of clinical T1 non-small cell lung cancer: a brief review of possible methodologies and controversies.Frontiers in oncology · 2024Review
- CT morphological features and histogram parameters to predict micropapillary or solid components in stage IA lung adenocarcinoma.Frontiers in oncology · 2024Article
- Establishment and validation of nomograms for predicting survival of lung invasive adenocarcinoma based on the level of pathological differentiation: a SEER cohort-based analysis.Translational cancer research · 2023Article
- [Advances in the Study of Invasive Non-mucinous Adenocarcinoma with Different Pathological Subtypes].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023Review
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the PET/CT findings in lung invasive adenocarcinoma with minor components of micropapillary or solid contents and its association with lymph node metastasis. MATERIALS AND
methodsA total of 506 lung invasive adenocarcinoma (≤ 3 cm) patients who underwent a PET/CT examination and resection surgery were included. According to the proportion of solid/micropapillary components, the patients were classified into three groups: solid/micropapillary-negative (SMPN) (n = 258), solid/micropapillary-minor (SMPM; > 5% not predominant) (n = 158) and solid/micropapillary-predominant (SMPP; > 5% most dominant) (n = 90). The patients' PET/CT findings, including SUVmax, MTV, TLG and CT characteristics, and other clinical factors were compared by one-way ANOVA test. Logistic regression analysis was done to identify the most predictive findings for lymph node metastasis.
resultsThe value of SUVmax, MTV, TLG and tumor size was highest in SMPP group, followed by SMPM and SMPN group (P < 0.001).The areas under the curve for SUVmax, MTV and TLG for node metastasis were 0.822, 0.843 and 0.835, respectively. Univariate analysis found that the SMPP and SMPM group had more lymph node metastasis than the SMPN group (P < 0.001). Furthermore, the lymph node metastasis group had higher CEA, SUVmax, MTV, TLG, tumor size and more pleural invasion (P < 0.001). Logistic regression analysis found that SMPP pathological type, SMPM pathological type, higher CEA and male patients were risk factors for lymph node metastasis (P < 0.01).
conclusionsLung invasive adenocarcinoma with micropapillary or solid contents had higher SUVmax, MTV, TLG and tumor size and was associated with lymph node metastasis, even if they were not predominant.
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