ArticleEnvironmental science and pollution research international2020
Red beetroot extract mitigates chlorpyrifos-induced reprotoxicity associated with oxidative stress, inflammation, and apoptosis in rats.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Research progress on the role and mechanism of DNA damage repair in germ cell development.Frontiers in endocrinology · 2023Pooled it
- The therapeutic potential of red beetroot (Food science & nutrition · 2024Article
- Neurotoxic effects of type II-diabetes mellitus and the possible preventive effects of olive leaves supplement in male rats.Open veterinary journal · 2024Article
- Article
- Olive Leaf Extract Attenuates Chlorpyrifos-Induced Neuro- and Reproductive Toxicity in Male Albino Rats.Life (Basel, Switzerland) · 2022Article
- Pesticide Exposure in Relation to the Incidence of Abnormal Glucose Regulation: A Retrospective Cohort Study.International journal of environmental research and public health · 2022Article
- Beetroot as a functional food with huge health benefits: Antioxidant, antitumor, physical function, and chronic metabolomics activity.Food science & nutrition · 2021Review
- Study on the Efficacy and Mechanism ofNutrients · 2021Article
- Molecular, Immunomodulatory, and Histopathological Role of Mesenchymal Stem Cells and Beetroot Extract on Cisplatin Induced Testicular Damage in Albino Rats.Animals : an open access journal from MDPI · 2021Article
- Silver nanoparticles-induced nephrotoxicity in rats: the protective role of red beetroot (Beta vulgaris) juice.Environmental science and pollution research international · 2020Article
- Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract in rats: highlighting the antioxidant, anti-inflammatory, and anti-apoptotic activities.Environmental science and pollution research international · 2020Article
- Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women.Bioscience reports · 2020Article
- Red Beetroot Extract Abrogates Chlorpyrifos-Induced Cortical Damage in Rats.Oxidative medicine and cellular longevity · 2020Article
- Ziziphus spina-christi leaf extract attenuates mercury chloride-induced testicular dysfunction in rats.Environmental science and pollution research international · 2020Article
- Role of Beetroot (International journal of nanomedicine · 2020Article
- Antagonistic Efficacy of Luteolin against Lead Acetate Exposure-Associated with Hepatotoxicity is Mediated via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activities.Antioxidants (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
The goal of our investigation is to evaluate the potential protective efficacy of red beetroot extract (RBR) against testicular toxicity produced by CPF in rats. CPF exposure decreased the weight of testis and the levels of luteinizing hormone, follicle stimulating hormone and testosterone. CPF impaired also the oxidative status in favor of pro-oxidant molecules in the testicular tissue. Additionally, CPF stimulated the production of pro-inflammatory cytokines and their gene expression. Concomitantly, an apoptotic cascade has been observed upon CPF intoxication. However, RBR administration protected the testis tissue through modulating the hormonal level, inhibiting the oxidative damage, inflammation and the apoptotic responses following CPF intoxication. The obtained data recommend the use of RBR to prevent CPF-induced testicular damage via antioxidant, anti-inflammatory, and anti-apoptotic pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.