Evidence map›Paper›PMID 31823232›Full record

ReviewOphthalmology and therapy2020

Current Understanding of the Progression and Management of Thyroid Associated Orbitopathy: A Systematic Review.

Nickisa M Hodgson, Fatemeh Rajaii

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Ophthalmology and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Management of Eyelid Pathologies That Cause Corneal Lesions.Advances in experimental medicine and biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nickisa M HodgsonWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fatemeh RajaiiWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. frajaii1@jhmi.edu.ORCID http://orcid.org/0000-0002-1012-2293

Funding

Identification of pathways involved in orbital adipogenesis using functional genomicsK08EY027093 · NEI · JOHNS HOPKINS UNIVERSITY · PI RAJAII, FATEMEH · 2016 to 2020
$862k
National Eye Institute (US) K08EY027093NEI NIH HHS K08 EY027093
6 · The paper itself

Abstract

Thyroid associated orbitopathy (TAO) is a common diagnosis encountered by ophthalmologists and oculoplastic surgeons. TAO has a varying clinical presentation that can include upper eyelid retraction, restrictive strabismus, proptosis, exposure keratopathy, and optic neuropathy. In this review, we discuss the most recent literature on and the current understanding of the pathophysiology of TAO. We also review available and potential future treatment options for the management of TAO.

Indexed as

CorticosteroidGraves’ orbitopathyRituximabSeleniumTeprotumumabThyroid associated orbitopathyThyroid eye diseaseTocilizumab

Identifiers

PMID31823232
PMCPMC7054489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.