Evidence map›Paper›PMID 31823076›Full record

ArticleEuropean journal of pediatrics2020

Pharmaco-epidemiological research on herbal medicinal products in the paediatric population: data from the PhytoVIS study.

Karen Nieber, Esther Raskopf, Johanna Möller, Olaf Kelber, Robert Fürst, Kija Shah-Hosseini, Jaswinder Singh, Karin Kraft, Ralph Mösgens

Open access · hybridAbstract read
In one paragraph

Article in European journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Karen NieberInstitute of Pharmacy, University of Leipzig, Brüderstr. 34, 04103, Leipzig, Germany. nieberkaren@gmx.de.
Esther RaskopfInstitute of Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Johanna MöllerBayer Consumer Health, Research & Development, Phytomedicines Supply and Development Center, Steigerwald Arzneimittelwerk GmbH, Havelstr. 5, 64295, Darmstadt, Germany.
Olaf KelberKooperation Phytopharmaka GbR, Plittersdorfer Str. 218, 53173, Bonn, Germany.
Robert FürstKooperation Phytopharmaka GbR, Plittersdorfer Str. 218, 53173, Bonn, Germany.
Kija Shah-HosseiniKooperation Phytopharmaka GbR, Plittersdorfer Str. 218, 53173, Bonn, Germany.
Jaswinder SinghInstitute of Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Karin KraftKooperation Phytopharmaka GbR, Plittersdorfer Str. 218, 53173, Bonn, Germany.
Ralph MösgensInstitute of Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
University of Cologne · DEBayer (Germany) · DEGoethe University Frankfurt · DELeipzig University · DEPresbyterian College · USUniversity of Rostock · DE

Funding

Kooperation Phytopharmaka GbR,Bonn, Germany 0
6 · The paper itself

Abstract

In paediatrics, clinical study data are limited, especially on herbal medicinal products. To address this gap, 2063 datasets from the paediatric population were evaluated in the PhytoVIS data base. By screening for paediatric data, information on indication, gender, treatment, co-medication and tolerability were evaluated. The majority of patients was treated because of common cold, fever, digestive complaints, skin diseases, sleep disturbances and anxiety. The perceived effect of the therapy was rated in 84% of the patients as very good or good without adverse events. The data shed light on a still neglected field of phyto-pharmacotherapy by giving information on the use of herbal medicines in an unselected cohort of paediatric patients. The results confirm the good clinical effects and safety of herbal medicinal products in this patient population and show that they are widely used in Germany.What is Known:• In Germany, about 85% of children receive one or more herbal medicinal products per year.• Despite international initiatives to promote clinical research in paediatrics, there are still many gaps of knowledge in the use of drugs in paediatrics.What is New:• The PhytoVIS project evaluated 2063 data sets from the paediatric population using herbal medicinal products.• The majority of patients was treated because of common cold, fever, digestive complaints, skin diseases, sleep disturbances and anxiety, and 84% of the patients rated the therapy as very good or good without adverse events.

Indexed as

ChildChild, PreschoolDatasets as TopicFemaleGermanyHerbal MedicineHumansInfantInfant, NewbornMalePhytotherapyPractice Patterns, Physicians'Retrospective StudiesSelf MedicationSurveys and QuestionnairesTreatment OutcomeAdolescentsChildrenHerbal medicinal productsPharmaco-epidemiological studyPhytoVIS project

Identifiers

PMID31823076
PMCPMC7028796
OpenAlexW2996016890

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.