Evidence map›Paper›PMID 31822819›Full record

ArticleMolecular psychiatry2021

Expression and co-expression of serotonin and dopamine transporters in social anxiety disorder: a multitracer positron emission tomography study.

Olof R Hjorth, Andreas Frick, Malin Gingnell, Johanna M Hoppe, Vanda Faria, Sara Hultberg, Iman Alaie, Kristoffer N T Månsson, Kurt Wahlstedt, My Jonasson and 4 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. [Association Between Social Anxiety Symptoms and Brain Metabolism].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Anxiety and depression: A top-down, bottom-up model of circuit function.Annals of the New York Academy of Sciences · 2023
    Review
  14. Striatal dopamine transporter and receptor availability correlate with relative cerebral blood flow measured with [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Olof R HjorthDepartment of Psychology, Uppsala University, Uppsala, Sweden. olof.hjorth@psyk.uu.se.
Andreas FrickDepartment of Psychology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0003-2516-9075
Malin GingnellDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Johanna M HoppeDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Vanda FariaDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Sara HultbergDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Iman AlaieDepartment of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden.
Kristoffer N T MånssonCentre for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.
Kurt WahlstedtDepartment of Psychology, Uppsala University, Uppsala, Sweden.
My JonassonDepartment of Surgical Sciences-Nuclear medicine and PET, Uppsala University, Uppsala, Sweden.
Mark LubberinkDepartment of Surgical Sciences-Nuclear medicine and PET, Uppsala University, Uppsala, Sweden.
Gunnar AntoniDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Mats FredriksonDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Tomas FurmarkDepartment of Psychology, Uppsala University, Uppsala, Sweden.
Uppsala University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin and dopamine are putatively involved in the etiology and treatment of anxiety disorders, but positron emission tomography (PET) studies probing the two neurotransmitters in the same individuals are lacking. The aim of this multitracer PET study was to evaluate the regional expression and co-expression of the transporter proteins for serotonin (SERT) and dopamine (DAT) in patients with social anxiety disorder (SAD). Voxel-wise binding potentials (BP

Indexed as

Phobia, SocialSerotoninBrainDopamineDopamine Plasma Membrane Transport ProteinsHumansPositron-Emission TomographySerotonin Plasma Membrane Transport ProteinsDopamineDopamine Plasma Membrane Transport ProteinsSerotoninSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID31822819
OpenAlexW2995431973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.