ArticleScientific reports2019
Transcranial direct current stimulation (tDCS) over vmPFC modulates interactions between reward and emotion in delay discounting.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- A multinational analysis of how emotions relate to economic decisions regarding time or risk.Nature human behaviour · 2024Pooled it
- Theta tACS impairs episodic memory more than tDCS.Scientific reports · 2023Trial
- The functional connectivity between the dorsolateral prefrontal cortex and the medial prefrontal cortex underlying the association between self-control and delay discounting.Brain structure & function · 2025Article
- Neuromodulation of risk and reward processing during decision making in individuals with general anxiety disorder (GAD).Scientific reports · 2025Article
- Direct stimulation of anterior insula and ventromedial prefrontal cortex disrupts economic choices.Nature communications · 2024Article
- Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder.Journal of clinical medicine · 2023Review
- Neural Correlates of Delay Discounting in the Light of Brain Imaging and Non-Invasive Brain Stimulation: What We Know and What Is Missed.Brain sciences · 2023Review
- Modulated effectiveness of rehabilitation motivation by reward strategies combined with tDCS in stroke: study protocol for a randomized controlled trial.Frontiers in neurology · 2023Article
- Transcranial direct current stimulation (tDCS) over the orbitofrontal cortex reduces delay discounting.Frontiers in behavioral neuroscience · 2023Article
- Noninvasive stimulation of the ventromedial prefrontal cortex modulates rationality of human decision-making.Scientific reports · 2022Article
- Anodal tDCS over the medial prefrontal cortex enhances behavioral adaptation after punishments during reversal learning through increased updating of unchosen choice options.Cerebral cortex communications · 2022Article
- Brain Stimulation for Emotion Regulation in Adolescents With Psychiatric Disorders: Study Protocol for a Clinical-Transdiagnostical, Randomized, Triple-Blinded and Sham-Controlled Neurotherapeutic Trial.Frontiers in psychiatry · 2022Article
- Is value-based choice repetition susceptible to medial frontal transcranial direct current stimulation (tDCS)? A preregistered study.Cognitive, affective & behavioral neuroscience · 2021Article
- Sensation-Seeking and Impulsivity in Athletes with Sport-Related Concussion.Current psychiatry reports · 2021Review
- Differences in resting-state functional connectivity according to the level of impulsiveness in patients with internet gaming disorder.Journal of behavioral addictions · 2021Article
- Interactions between decision-making and emotion in behavioral-variant frontotemporal dementia and Alzheimer's disease.Social cognitive and affective neuroscience · 2020Article
- Hot and cold executive functions in the brain: A prefrontal-cingular network.Brain and neuroscience advancesReview
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delay discounting requires computing trade-offs between immediate-small rewards and later-larger rewards. Negative and positive emotions shift decisions towards more or less impulsive responses, respectively. Models have conceptualized this trade-off by describing an interplay between "emotional" and "rational" processes, with the former involved during immediate choices and relying on the ventromedial prefrontal cortex (vmPFC), and the latter involved in long-term choices and relying on the dorsolateral prefrontal cortex (dlPFC). Whether stimulation of the vmPFC modulates emotion-induced delay discounting remains unclear. We applied tDCS over the vmPFC in 20 healthy individuals during a delay discounting task following an emotional (positive, negative) or neutral induction. Our results showed that cathodal tDCS increased impulsivity after positive emotions in high impulsivity trials. For low impulsivity trials, anodal tDCS decreased impulsivity following neutral induction compared with emotional induction. Our findings demonstrate that the vmPFC integrates reward and emotion most prominently in situations of increased impulsivity, whereas when higher cognitive control is required the vmPFC appears to be less engaged, possibly due to recruitment of the dlPFC. Understanding how stimulation and emotion influence decision-making at the behavioural and neural levels holds promise to develop interventions to reduce impulsivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.