Evidence map›Paper›PMID 31822586›Full record

ArticlemBio2019

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression.

Claire E Turner, Matthew T G Holden, Beth Blane, Carolyne Horner, Sharon J Peacock, Shiranee Sriskandan

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Genomic interrogation of invasive group AThe Lancet regional health. Western Pacific · 2025
    Article
  5. The group AInfection and immunity · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Molecular characterization ofMicrobial genomics · 2024
    Article
  11. Article
  12. EmergentInfection and immunity · 2024
    Article
  13. Article
  14. Outbreak ofMicrobiology spectrum · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Group AJournal of clinical medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Claire E TurnerMolecular Biology & Biotechnology, The Florey Institute, University of Sheffield, Sheffield, United Kingdom c.e.turner@sheffield.ac.uk.ORCID 0000-0002-4458-9748
Matthew T G HoldenPathogen Genomics, The Wellcome Trust Sanger Institute, Cambridge, United Kingdom.ORCID 0000-0002-4958-2166
Beth BlaneDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Carolyne HornerBritish Society for Antimicrobial Chemotherapy, Birmingham, United Kingdom.
Sharon J PeacockDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Shiranee SriskandanDepartment of Infectious Disease, Imperial College London, London, United Kingdom.ORCID 0000-0002-5214-4941
Imperial College London · GBUniversity of Cambridge · GBBritish Society for Antimicrobial Chemotherapy · GBUniversity of St Andrews · GB

Funding

Medical Research Council G0800777Wellcome Trust 208765/Z/17/Z
6 · The paper itself

Abstract

Gene transfer and homologous recombination in

Indexed as

Antigens, BacterialBacterial CapsulesBacterial Outer Membrane ProteinsBacterial ProteinsBase SequenceEnglandGenotypeHumansNAD+ NucleosidaseStreptococcal InfectionsStreptococcus pyogenesStreptolysinsToxins, BiologicalVirulence FactorsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsNAD+ Nucleosidasestreptolysin OStreptolysinsToxins, BiologicalVirulence Factorsconvergent evolutiongroup A Streptococcushomologous recombinationhyaluronic acid capsuleNADaseStreptococcus pyogenesstreptolysin Owhole-genome sequencing

Identifiers

PMID31822586
PMCPMC6904876
OpenAlexW2995693140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.