Evidence map›Paper›PMID 31822583›Full record

ArticlemBio2019

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum.

Laure Dumont, Mark B Richardson, Phillip van der Peet, Danushka S Marapana, Tony Triglia, Matthew W A Dixon, Alan F Cowman, Spencer J Williams, Leann Tilley, Malcolm J McConville and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  10. Carbonyl Stress in Red Blood Cells and Hemoglobin.Antioxidants (Basel, Switzerland) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Laure DumontDepartment of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia.
Mark B RichardsonSchool of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia.
Phillip van der PeetSchool of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia.
Danushka S MarapanaThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Tony TrigliaThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Matthew W A DixonDepartment of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia.ORCID 0000-0001-9732-9686
Alan F CowmanThe Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Spencer J WilliamsSchool of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia.
Leann Tilley *Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia.ORCID 0000-0001-9910-0199
Malcolm J McConville *Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia malcolmm@unimelb.edu.au simon.cobbold@unimelb.edu.au.ORCID 0000-0002-7107-7887
Simon A Cobbold *Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia malcolmm@unimelb.edu.au simon.cobbold@unimelb.edu.au.
The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Members of the haloacid dehalogenase (HAD) family of metabolite phosphatases play an important role in regulating multiple pathways in

Indexed as

AntimalarialsCarbonDrug ResistanceFosfomycinGlycolysisHumansLactatesMalaria, FalciparumPhosphoric Monoester HydrolasesPlasmodium falciparumSugar Acids2-phospholactic acid4-phosphoerythronateAntimalarialsCarbonFosfomycinfosmidomycinLactatesphosphoglycolate phosphatasePhosphoric Monoester HydrolasesSugar AcidsantimalarialCRISPRfosmidomycinglycolysisisoprenoidmetabolic regulationmetabolismmetabolomicsparasitologypentosePlasmodium falciparum

Identifiers

PMID31822583
PMCPMC6904873
OpenAlexW2996632776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.