Evidence map›Paper›PMID 31822560›Full record

ArticleThe Journal of biological chemistry2020

Yunrong Gao, Dongdong Cao, Hyunjun Max Ahn, Anshuman Swain, Shaylan Hill, Claire Ogilvie, Matthew Kurien, Taha Rahmatullah, Bo Liang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yunrong GaoDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.ORCID 0000-0001-6787-2397
Dongdong CaoDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.ORCID 0000-0002-2031-9321
Hyunjun Max AhnDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Anshuman SwainDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Shaylan HillDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Claire OgilvieDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Matthew KurienDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Taha RahmatullahDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322.
Bo LiangDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia 30322 bo.liang@emory.edu.ORCID 0000-0002-5617-9228
Emory University · US

Funding

Structure and Regulation of The Respiratory Syncytial Virus PolymeraseR01GM130950 · NIGMS · EMORY UNIVERSITY · PI Bo Liang · 2019 to 2026
$3.3M
NIGMS NIH HHS R01 GM130950
6 · The paper itself

Abstract

The templates for transcription and replication by respiratory syncytial virus (RSV) polymerase are helical nucleocapsids (NCs), formed by viral RNAs that are encapsidated by the nucleoprotein (N). Proper NC assembly is vital for RSV polymerase to engage the RNA template for RNA synthesis. Previous studies of NCs or nucleocapsid-like particles (NCLPs) from RSV and other nonsegmented negative-sense RNA viruses have provided insights into the overall NC architecture. However, in these studies, the RNAs were either random cellular RNAs or average viral genomic RNAs. An in-depth mechanistic understanding of NCs has been hampered by lack of an

Indexed as

Genome, ViralHumansNucleocapsidNucleoproteinsRespiratory Syncytial Virus, HumanRNA, ViralVirus ReplicationNucleoproteinsRNA, ViralchromatographyEMgenome replicationnegative-strand RNA virusnucleocapsid-like particle (NCLP)nucleocapsid (NC)nucleoprotein (N)protein assemblyrespiratory syncytial virus (RSV)RNA–protein interaction

Identifiers

PMID31822560
PMCPMC6970927
OpenAlexW2995675501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.