Evidence map›Paper›PMID 31822501›Full record

ArticleCMAJ open

Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study.

Danielle M Nash, Jade S Dirk, Eric McArthur, Michael E Green, Baiju R Shah, Jennifer D Walker, Mary Beaucage, Carmen R Jones, Amit X Garg

Open access · diamondAbstract readComment
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Impact of a screen, triage and treat program for identifying chronic disease risk in Indigenous children.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Observational
  7. Impact of point-of-care screening for hypertension, diabetes and progression of chronic kidney disease in rural Manitoba Indigenous communities.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  8. Article
  9. Article
  10. Monitoring, treatment and control of blood glucose and lipids in Ontario First Nations people with diabetes.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Danielle M NashICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont. Danielle.nash@ices.on.ca.
Jade S DirkICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Eric McArthurICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Michael E GreenICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Baiju R ShahICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Jennifer D WalkerICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Mary BeaucageICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Carmen R JonesICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Amit X GargICES Western (Nash, Dirk, McArthur, Garg); Department of Epidemiology and Biostatistics (Nash), Western University, London Ont.; ICES Central (Shah, Walker), Toronto, Ont.; Department of Infectious Diseases (Dirk), Nova Scotia Health Authority, Halifax, NS; ICES Queen's (Green); Department of Family Medicine (Green), Queen's University, Kingston, Ont.; Department of Medicine (Shah), University of Toronto, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.; Patient and Family Advisory Council (Beaucage), Ontario Renal Network; the Chiefs of Ontario (Jones), Toronto, Ont.; Department of Medicine (Garg), Western University, London, Ont.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnd-stage kidney disease is a serious complication of diabetes. We describe the prevalence of chronic kidney disease, prevalence and incidence of end-stage kidney disease and quality of care of early-stage chronic kidney disease for First Nations people with diabetes compared to other Ontarians with diabetes.

methodsWe conducted a retrospective cohort study in Ontario using linked administrative data at ICES. We included adults with incident diabetes between 1994 and 2014, and used laboratory values to identify kidney disease and quality indicators for care for early-stage disease. We compared measures in First Nations people to those in other people in Ontario, and used direct age and sex standardization. We used Cox proportional hazards regression to compare the incidence of end-stage kidney disease between groups.

resultsOur study included 21 968 First Nations people with diabetes. The age- and sex-standardized prevalence of chronic kidney disease was higher for First Nations people than for other Ontarians (20.7% v. 18.4%), as was the prevalence of end-stage kidney disease (2.9% v. 1.0%). The incidence of end-stage kidney disease was higher among First Nations people than among other people in Ontario (9.3 v. 4.7 events per 10 000 person-years; age- and sex-adjusted hazard ratio 2.23, 95% confidence interval 1.72-2.89). The 2 groups were similarly likely to receive recommended medications, but First Nations people were less likely to receive laboratory tests for their kidney disease.

interpretationDespite receiving similar quality of care for early-stage kidney disease, First Nations people with diabetes had higher rates of end-stage kidney disease than other Ontarians. Further research is needed to better understand contributing factors to help inform future interventions.

Identifiers

PMID31822501
PMCPMC7015672
OpenAlexW2995809427

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.