ArticleBJGP open2019
Patient decision aids for antidepressant use in pregnancy: a pilot randomised controlled trial in the UK.
Article in BJGP open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02492009 (Patient Decision Aid), which is not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Patient Decision Aid (PDA) for Antidepressant Use In Pregnancy: a Pilot RCT
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Association between antidepressant use during pregnancy and miscarriage: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- Trends, challenges, and priorities for shared decision making in mental health: The first umbrella review.The International journal of social psychiatry · 2023Pooled it
- Shared decision-making interventions for people with mental health conditions.The Cochrane database of systematic reviews · 2022Pooled it
- The effectiveness of decision aids for pregnancy related decision-making in women with pre-pregnancy morbidity; systematic review and meta-analysis.BMC pregnancy and childbirth · 2022Pooled it
- Motherhood choice in multiple sclerosis (MoMS) - Pilot trial of web-based decision support.PloS one · 2026Trial
- Effectiveness of a web-based decision aid for patients with Generalised Anxiety Disorder in Spain: a randomised controlled trial.BMJ health & care informatics · 2025Trial
- Development of a Cocreated Decision Aid for Patients With Depression-Combining Data-Driven Prediction With Patients' and Clinicians' Needs and Perspectives: Mixed Methods Study.Journal of participatory medicine · 2025Article
- Barriers to help-seeking for postpartum depression mapped onto the socio-ecological model and recommendations to address barriers.Frontiers in global women's health · 2024Article
- Developing and evaluating an interprofessional shared decision-making care model for patients with perinatal depression in maternal care in urban China: a study protocol.BMC primary care · 2023Article
- Toward Shared Decision-Making in Degenerative Cervical Myelopathy: Protocol for a Mixed Methods Study.JMIR research protocols · 2023Article
- Comparison of analog and digital patient decision aids for the treatment of depression: a scoping review.Frontiers in digital health · 2023Article
- The development of a patient decision aid to reduce decisional conflict about antidepressant use in pregnancy.BMC medical informatics and decision making · 2022Article
- Treatment of Peripartum Depression with Antidepressants and Other Psychotropic Medications: A Synthesis of Clinical Practice Guidelines in Europe.International journal of environmental research and public health · 2022Review
- Effectiveness of patient decision aids in women considering psychotropic medication use during pregnancy: a literature review.Archives of women's mental health · 2021Review
- "I know my body better than you:" patient focus groups to inform a decision aid on oral corticosteroid use during pregnancy.Pharmacoepidemiology and drug safety · 2021Article
- Perinatal mental health: a review of progress and challenges.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundDecision-making regarding antidepressant use in pregnancy is challenging, given the uncertain evidence base on the benefits and risks for women and their children. Patient decision aids (PDAs) can improve shared decision-making for complex health decisions but no evidence-based PDAs exist for antidepressant use in pregnancy.
aimTo assess the feasibility of a full-scale randomised controlled trial (RCT) to evaluate the efficacy of an electronic PDA on antidepressant use in pregnancy. DESIGN &
settingA UK-based pilot parallel-group RCT.
methodThe study recruited women whose clinicians recommended an antidepressant for depression in a current or planned pregnancy, and who were uncertain about antidepressant use while pregnant. Women were recruited via clinician or self-referral, and randomised to online access to the PDA or online access to standard resource list, with primary follow-up at 4 weeks and longer-term follow-up. The primary outcome was protocol feasibility (recruitment target of 50 women and follow-up rate of 80%). Outcome measures for a future full-scale RCT included the decisional conflict scale (DCS).
resultsFifty-one women were recruited with a follow-up rate of 90.2% at 4 weeks. The PDA received good overall satisfaction ratings (mean 4.2/5). Analysis of covariance (ANCOVA) indicated a small improvement in decisional conflict at 4 weeks, accounting for baseline scores (DCS regression coefficient = -3.5, 95% confidence intervals [CI = -12.6 to 5.6]).
conclusionThis pilot RCT for an electronic PDA on antidepressant use in pregnancy showed that the study protocol was feasible, with high rates of participant satisfaction among those randomised to the PDA.
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